5330-29-0

• 常用中文名：1,6-Hexanediamine,N1,N1-diethyl-N6-(6-methoxy-4-methyl-8-quinolinyl)-, hydrochloride (1:2)
• 常用英文名：1,6-Hexanediamine,N1,N1-diethyl-N6-(6-methoxy-4-methyl-8-quinolinyl)-, hydrochloride (1:2)
• CAS号：5330-29-0
• 分子式：C₂₁H₃₄ClN₃O
• 分子量：379.96700
• 发布时间：2017-03-21 03:37:40
• 更新时间：2025-08-27 17:37:19

名称

• 英文名: 8-(6-diethylaminohexylamino)-6-methoxy-4-methylquinoline, dihydrochloride
• 英文别名: N,N-Diethyl-N'-(6-methoxy-4-methyl-8-quinolinyl)-1,6-hexanediamine,Dihydrochloride; 6-methoxy-8-(diethylaminohexylamino)lepidine dihydrochloride; sitamaquine dihydrochloride; N,N-diethyl-N'-(6-methoxy-4-methyl-8-quinolyl)hexane-1,6-diamine dihydrochloride; 6-methoxy-8-(6-diethylaminohexylamino)lepidine dihydrochloride; 8-(6-diethylaminohexylamino)-6-methoxy-4-methylquinoline dihydrochloride

物化性质

• 沸点: 502.8ºC at 760mmHg
• 分子式: C₂₁H₃₄ClN₃O
• 分子量: 379.96700
• 闪点: 257.9ºC
• 精确质量: 379.23900
• PSA: 37.39000
• LogP: 5.74090

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : MO1294500 CHEMICAL NAME : 1,6-Hexanediamine, N,N-diethyl-N(sup 1)-(6-methoxy-4-methyl-8-quinolinyl)-, dihydrochloride CAS REGISTRY NUMBER : 5330-29-0 LAST UPDATED : 199801 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C21-H33-N3-O.2Cl-H MOLECULAR WEIGHT : 416.49 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1252 mg/kg/13W-I TOXIC EFFECTS : Endocrine - changes in spleen weight Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases REFERENCE : DDREDK Drug Development Research. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1981- Volume(issue)/page/year: 40,75,1997 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 313 mg/kg/13W-I TOXIC EFFECTS : Endocrine - changes in spleen weight Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases REFERENCE : DDREDK Drug Development Research. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1981- Volume(issue)/page/year: 40,75,1997 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 480 mg/kg SEX/DURATION : female 6-15 day(s) after conception TOXIC EFFECTS : Reproductive - Maternal Effects - other effects REFERENCE : TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 3,65,1983