39270-39-8

• 常用中文名：2,3-二氢-1,4-苯并二氧甲醇
• 常用英文名：2,3-Dihydro-1,4-benzodioxin-6-ylmethanol
• CAS号：39270-39-8
• 分子式：C₉H₁₀O₃
• 分子量：166.174
• 发布时间：2018-12-09 19:48:05
• 更新时间：2024-01-02 09:30:50

名称

• 中文名: 2,3-二氢-1,4-苯并二氧甲醇
• 英文名: (2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)methanol
• 中文别名: 苯并二氧六环-6-甲醇
• 英文别名: (2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methanol; 1,4-Benzodioxin-6-methanol, 2,3-dihydro-; 2,3-Dihydro-1,4-benzodioxin-6-ylmethanol

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 301.2±21.0 °C at 760 mmHg
• 分子式: C₉H₁₀O₃
• 分子量: 166.174
• 闪点: 136.0±22.1 °C
• 精确质量: 166.062988
• PSA: 38.69000
• LogP: 0.70
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.572
• 储存条件: 室温

MSDS

Name: 2 3-Dihydro-1 4-benzodioxin-6-ylmethanol 97% Material Safety Data Sheet Synonym: 6-Hydroxymethylbenzodioxan CAS: 39270-39-8 Section 1 - Chemical Product MSDS Name:2 3-Dihydro-1 4-benzodioxin-6-ylmethanol 97% Material Safety Data Sheet Synonym:6-Hydroxymethylbenzodioxan Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 39270-39-8 2,3-dihydro-1,4-benzodioxin-6-ylmethan 254-396-7 Hazard Symbols: None Listed. Risk Phrases: None Listed. Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Not available. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: May cause respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 39270-39-8: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Liquid Color: Not available. Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: 129 deg C @0.2mmHg Freezing/Melting Point: Not available. Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Not available. Solubility in water: Specific Gravity/Density: Molecular Formula: C9H10O3 Molecular Weight: 166 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents, bases. Hazardous Decomposition Products: Carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 39270-39-8 unlisted. LD50/LC50: Not available. Carcinogenicity: 2,3-dihydro-1,4-benzodioxin-6-ylmethanol - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. Risk Phrases: Safety Phrases: WGK (Water Danger/Protection) CAS# 39270-39-8: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 39270-39-8 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 39270-39-8 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xi: Irritant;
• 风险声明 (欧洲): 36/37/38
• 安全声明 (欧洲): 26-36/37/39
• 海关编码: 2932999099

合成路线

29668-44-8 ~99% 39270-39-8

文献：SMITHKLINE BEECHAM P.L.C. Patent: WO2003/87098 A1, 2003 ; Location in patent: Page/Page column 43 ;

20825-87-0 ~88% 39270-39-8

文献：Feng; Liu; Dai; Yang; Tu Synthetic Communications, 2001 , vol. 31, # 12 p. 1875 - 1877

4442-54-0 ~66% 39270-39-8

文献：Marugan, Juan J.; Zheng, Wei; Motabar, Omid; Southall, Noel; Goldin, Ehud; Westbroek, Wendy; Stubblefield, Barbara K.; Sidransky, Ellen; Aungst, Ronald A.; Lea, Wendy A.; Simeonov, Anton; Leister, William; Austin, Christopher P. Journal of Medicinal Chemistry, 2011 , vol. 54, # 4 p. 1033 - 1058

3943-89-3 ~% 39270-39-8

文献：Vertex Pharmaceuticals Incorported Patent: US2011/98311 A1, 2011 ;

上下游产品

上游产品  4
29668-44-8 20825-87-0 4442-54-0 3943-89-3
下游产品  1
79440-34-9

海关

海关编码	2932999099
中文概述	2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%