10429-82-0

• 常用中文名：N-苄基-N,N-双(2-氯乙基)胺盐酸盐
• 常用英文名：N-BENZYL-BIS(2-CHLOROETHYL)AMINE HYDROCHLORIDE
• CAS号：10429-82-0
• 分子式：C₁₁H₁₆Cl₃N
• 分子量：268.610
• 发布时间：2018-12-25 16:15:15
• 更新时间：2024-01-05 15:15:27

名称

• 中文名: N-苄基-N,N-双(2-氯乙基)胺盐酸盐
• 英文名: N-Benzyl-2-chloro-N-(2-chloroethyl)ethanamine hydrochloride
• 中文别名: N-苄基-双(2-氯乙基)甲胺盐酸盐; N-苄基-双邻氯乙基氨基盐酸盐; N-苄基-双邻氯乙基氨基盐酸盐; N,N-二-(2-氯乙基)苄胺盐酸盐
• 英文别名: Benzenemethanamine, N,N-bis(2-chloroethyl)-, hydrochloride (1:1); N-Benzyl-2-chloro-N-(2-chloroethyl)ethanamine hydrochloride; N-Benzyl-2-chloro-N-(2-chloroethyl)ethanamine hydrochloride (1:1); N-benzyl-2-chloro-N-(2-chloroethyl)ethanamine,hydrochloride; MFCD00185654; N-Benzyl-Bis(2-Chloroethyl)Amine Hydrochloride

物化性质

• 沸点: 242.6ºC at 760mmHg
• 熔点: 134-136ºC
• 分子式: C₁₁H₁₆Cl₃N
• 分子量: 268.610
• 闪点: 100.5ºC
• 精确质量: 267.034821
• PSA: 3.24000
• LogP: 3.76820
• 外观性状: 固体;White to Light yellow powder to crystal
• 蒸汽压: 0.02mmHg at 25°C
• 储存条件: 存放于惰性气体之中;避免湿气 (吸湿)

MSDS

Material Safety Data Sheet Section1. Identification of the substance N-Benzyl-bis(2-chloroethyl)amine, HCl Product Name: Synonyms: Section2. Hazards identification Harmful by inhalation, in contact with skin, and if swallowed. H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation P261:Avoid breathing dust/fume/gas/mist/vapours/spray Wear protective gloves/protective clothing/eye protection/face protection P280: P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing P304+P340:IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing P405:Store locked up Section3. Composition/information on ingredients. N-Benzyl-bis(2-chloroethyl)amine, HCl Ingredient name: CAS number:10429-82-0 Section4. First aid measures Immediately wash skin with copious amounts of water for at least 15 minutes while removing Skin contact: contaminated clothing and shoes. If irritation persists, seek medical attention. Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical attention. Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention. Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention. Ingestion: Section5. Fire fighting measures In the event of a fire involving this material, alone or in combination with other materials, use dry powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus should be worn. Section6. Accidental release measures Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national standards. Respiratory precaution:Wear approved mask/respirator Hand precaution:Wear suitable gloves/gauntlets Skin protection:Wear suitable protective clothing Eye protection:Wear suitable eye protection Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container for disposal. See section 12. Environmental precautions: Do not allow material to enter drains or water courses. Section7. Handling and storage Handling:This product should be handled only by, or under the close supervision of, those properly qualified in the handling and use of potentially hazardous chemicals, who should take into account the fire, health and chemical hazard data given on this sheet. Storage:Store in closed vessels. Section8. Exposure Controls / Personal protection Engineering Controls: Use only in a chemical fume hood. Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles. General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse. Section9. Physical and chemical properties Not specified Appearance: Boiling point:No data Melting point:No data Flash point:No data Density:No data Molecular formula:C11H15Cl2N.ClH Molecular weight:268.6 Section10. Stability and reactivity Conditions to avoid: Heat, flames and sparks. Materials to avoid: Oxidizing agents. Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, hydrogen chloride. Section11. Toxicological information No data. Section12. Ecological information No data. Section13. Disposal consideration Arrange disposal as special waste, by licensed disposal company, in consultation with local waste disposal authority, in accordance with national and regional regulations. Section14. Transportation information Non-harzardous for air and ground transportation. Section15. Regulatory information No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302, or have known CAS numbers that exceed the threshold reporting levels established by SARA Title III, Section 313. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DP1588000 CHEMICAL NAME : Benzylamine, N,N-bis(2-chloroethyl)-, hydrochloride CAS REGISTRY NUMBER : 10429-82-0 LAST UPDATED : 199410 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C11-H15-Cl2-N.Cl-H MOLECULAR WEIGHT : 268.63 WISWESSER LINE NOTATION : G2N2G1R &GH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 28 mg/kg TOXIC EFFECTS : Blood - changes in bone marrow (not otherwise specified) Blood - other changes Reproductive - Paternal Effects - testes, epididymis, sperm duct MUTATION DATA TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Mold - Aspergillus nidulans DOSE/DURATION : 2500 umol/L REFERENCE : SOGEBZ Soviet Genetics. English translation of GNKAA5. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.2- 1966- Volume(issue)/page/year: 6,220,1970

安全

• 危害码 (欧洲): Xi: Irritant;
• 海关编码: 2921499090

合成路线

101-32-6 ~97% 10429-82-0

文献：EP970046 B1, ; Page 46 ;

100-39-0 ~% 10429-82-0

文献：European Journal of Medicinal Chemistry, , vol. 75, p. 11 - 20

上下游产品

上游产品  2
101-32-6 100-39-0
下游产品  6
55-51-6 71258-18-9 7647-14-5 109254-16-2
7238-19-9 62226-74-8

海关

海关编码	2921499090
中文概述	2921499090 其他芳香单胺及衍生物及它们的盐. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%