613-21-8

• 常用中文名：6-羟基-2-甲基喹啉
• 常用英文名：2-Methyl-6-quinolinol
• CAS号：613-21-8
• 分子式：C₁₀H₉NO
• 分子量：159.185
• 发布时间：2018-09-10 20:46:17
• 更新时间：2024-01-01 22:42:30

名称

• 中文名: 6-羟基-2-甲基喹啉
• 英文名: 2-methylquinolin-6-ol
• 中文别名: 2-甲基-6-羟基喹啉
• 英文别名: 2-methyl-quinolin-6-ol; 6-hydroxy-2-methylquinoline; 6-hydroxy-2-quinaldine; 2-Methyl-6-hydroxyquinoline; 6-Quinolinol, 2-methyl-; 6-hydroxyquinaldine; 2-methyl-6-hydroxy-quinoline; 6-Quinolinol,2-methyl; 2-methylquinolin-6-ol; MFCD00047600; 2-Methyl-6-quinolinol

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 304.5±0.0 °C at 760 mmHg
• 熔点: 58-61°C
• 分子式: C₁₀H₉NO
• 分子量: 159.185
• 闪点: 142.3±22.3 °C
• 精确质量: 159.068420
• PSA: 33.12000
• LogP: 2.26
• 外观性状: 固体
• 蒸汽压: 0.0±0.6 mmHg at 25°C
• 折射率: 1.666
• 储存条件:

  贮存：

  将密器密封，储存密封的主藏器内，并放在阴凉， 干爽的位置。

• 稳定性:

  性质与稳定性：

  常温常压下，或不分解产物。

• 水溶解性: 可溶于：甲醇
• 分子结构:

  五、分子性质数据：

  1、 摩尔折射率：48.89

  2、 摩尔体积（m³/mol）：131.4

  3、 等张比容（90.2K）：357.9

  4、 表面张力（dyne/cm）：54.9

  5、 极化率（10 ^-24cm ³）：19.38

• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:1

  3.氢键受体数量:2

  4.可旋转化学键数量:0

  5.互变异构体数量:3

  6.拓扑分子极性表面积33.1

  7.重原子数量:12

  8.表面电荷:0

  9.复杂度:160

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

MSDS

Name: 2-Methylquinolin-6-ol 97% Material Safety Data Sheet Synonym: 6-Hydroxyquinaldin CAS: 613-21-8 Section 1 - Chemical Product MSDS Name:2-Methylquinolin-6-ol 97% Material Safety Data Sheet Synonym:6-Hydroxyquinaldin Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 613-21-8 2-Methylquinolin-6-ol 97% unlisted Hazard Symbols: XI Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 613-21-8: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: tan Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 198 - 200 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C10H9NO Molecular Weight: 159 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Oxidizing agents. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 613-21-8 unlisted. LD50/LC50: Not available. Carcinogenicity: 2-Methylquinolin-6-ol - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 613-21-8: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 613-21-8 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 613-21-8 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

生态学数据: 三、生态学数据： 1、其它有害作用：该物质对环境可能有危害，对水体应给予特别注意。

安全

• 危害码 (欧洲): Xi:Irritant;
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): S26-S36/37/39
• 海关编码: 2933499090

合成路线

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海关

海关编码	2933499090
中文概述	2933499090. 其他含喹琳或异喹啉环系的化合物〔但未进一步稠合的〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%