99592-39-9

• 常用中文名：硝酸舍他康唑
• 常用英文名：Sertaconazole nitrate
• CAS号：99592-39-9
• 分子式：C₂₀H₁₆Cl₃N₃O₄S
• 分子量：500.783
• 相关类别： 原料药 人工合成抗感染类药 抗真菌类药
• 发布时间：2018-09-16 12:28:26
• 更新时间：2026-07-01 19:01:27
• Sertaconazole硝酸盐是局部广谱的抗真菌剂,可作用于表皮和粘膜的感染。

名称

• 中文名: 硝酸舍他康唑
• 英文名: 1-[2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole,nitric acid
• 中文别名: 1-(2-((7-氯苯并[B]噻吩-3-基)甲氧基)-2-(2,4-二氯苯基)ETHYL)-1H-咪唑 硝酸盐; 硝酸舍他康唑 标准品; 1-[2-[(7-氯-3-苯并噻吩基)甲氧基]-2-(2,4-二氯苯基)乙基]咪唑; 1-[2-[(7-氯苯并噻吩-3-基)甲氧基]-2-(2,4-二氯苯基)乙基]咪唑; Sertaconazole nitrate试剂; 1-[2-[(7-氯-1-苯并噻吩-3-基)甲氧基]-2-(2,4-二氯苯基)乙基]咪唑; 硝酸舍他康唑/A1A; 1-[2-[(7-氯-1-苯并噻吩-3-基)甲氧基]-2-(2,4-二氯苯基)乙基]-1H-咪唑硝酸酯; 硝酸舍他康唑,10 MM DMSO 溶液; 1-(2-((7-氯苯并(b)噻吩-3-基)甲氧基)-2-(2,4-二氯苯基)乙基)-1H-咪唑硝酸盐
• 英文别名: Salpetersäure--1-{2-[(7-chlor-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorphenyl)ethyl}-1H-imidazol(1:1); 1-[2-[(7-chloro-3-benzothiophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole; Dermofix; 1H-Imidazole, 1-[2-[(7-chlorobenzo[b]thien-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-, nitrate (1:1); Extens; 1-[2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole; 1-(2-((7-Chlorobenzo[b]thiophen-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole nitrate; Fisderm; (RS)-1-[2-[(7-Chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4- dichlorophenyl)ethyl]-1H-imidazole nitrate; 1-(2-((7-Chlorobenzo(b)thien-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole mononitrate; 1-[2-[(7-Chlorobenzo[b]thien-3-yl)Methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-iMidazole Nitrate; Sertaconazole (nitrate); Sertaconazole nitrate, >=; DerMovit; Sertaconazole nitrate, 10 mM in DMSO; FI 7056; 1-(2-((7-Chlorobenzo[b]thien-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole mononitrate; Sertaconazole Mononitrate; SEROTONIN; NITRATE SERTACONAZOLE; Ginedermofix; Dermoseptic; Sertaconazole Nitrate (Ertaczo, Dermofix, Konzert, and Zalain); T56 BSJ IG D1OYR BG DG&1- AT5N CNJ &&HNO3; 1-[2-[(7-chlorobenzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole; Sertaconazle Nitrate; 1H-Imidazole, 1-(2-((7-chlorobenzo(b)thien-3-yl)methoxy)-2-(2,4-d; Sertaconazole nitrate CRS; 1-{2-[(7-Chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole nitrate (1:1); Ertaczo; Sertaconazole Nitrate In-House/Ph Eur/IP; sertaconazole nitrate; sertaconazole mononitrate; 1-[2-[(7-chloro-1-benzothien-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole nitrate; Sertaconazole NitrateQ: What is Sertaconazole Nitrate Q: What is the CAS Number of Sertaconazole Nitrate Q: What is the storage condition of Sertaconazole Nitrate Q: What e the applications of Sertaconazole Nitrate; Zalain; 1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole

物化性质

• 沸点: 614.1ºC at 760mmHg
• 熔点: 158-160°
• 分子式: C₂₀H₁₆Cl₃N₃O₄S
• 分子量: 500.783
• 闪点: 325.2ºC
• 精确质量: 498.992706
• PSA: 121.34000
• LogP: 7.19160
• 外观性状: 白色-米色粉末
• 储存条件: ?20°C
• 水溶解性: DMSO: soluble20mg/mL, clear

生物活性

• 描述: Sertaconazole硝酸盐是局部广谱的抗真菌剂,可作用于表皮和粘膜的感染。
• 相关类别:
  信号通路 >> 抗感染 >> 真菌
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Liebel, F., et al., Anti-inflammatory and anti-itch activity of sertaconazole nitrate. Arch Dermatol Res, 2006. 298(4): p. 191-9.

  [2]. Pfaller, M.A. and D.A. Sutton, Review of in vitro activity of sertaconazole nitrate in the treatment of superficial fungal infections. Diagn Microbiol Infect Dis, 2006. 56(2): p. 147-52.

  [3]. Sur, R., et al., Anti-inflammatory activity of sertaconazole nitrate is mediated via activation of a p38-COX-2-PGE2 pathway. J Invest Dermatol, 2008. 128(2): p. 336-44.

安全

• 危险品运输编码: NONH for all modes of transport
• 海关编码: 2934999090

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%