5462-86-2

• 常用中文名：6-氯-9-乙基-9h-嘌呤
• 常用英文名：6-chloro-9-ethyl-purine
• CAS号：5462-86-2
• 分子式：C₇H₇ClN₄
• 分子量：182.61000
• 发布时间：2016-11-11 11:50:59
• 更新时间：2024-01-10 22:36:01

名称

• 中文名: 6-氯-9-乙基-9h-嘌呤
• 英文名: 6-Chloro-9-ethylpurine
• 英文别名: F2124-0079; 6-Chlor-9-aethyl-9H-purin; 6-Chlor-9-aethyl-purin; 9H-Purine,6-chloro-9-ethyl; 6-chloro-9-ethyl-purine; 6-chloro-9-ethyl-9H-purine; 9-Aethyl-6-chlor-9H-purin; 9-ethyl-6-chloropurine

物化性质

• 密度: 1.5g/cm3
• 沸点: 326.9ºC at 760 mmHg
• 分子式: C₇H₇ClN₄
• 分子量: 182.61000
• 闪点: 151.5ºC
• 精确质量: 182.03600
• PSA: 43.60000
• LogP: 1.49960
• 折射率: 1.705
• 储存条件: 室温

MSDS

Name: 6-Chloro-9-Ethyl-9H-Purine Material Safety Data Sheet Synonym: None Known CAS: 5462-86-2 Section 1 - Chemical Product MSDS Name:6-Chloro-9-Ethyl-9H-Purine Material Safety Data Sheet Synonym:None Known Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 5462-86-2 6-Chloro-9-Ethyl-9H-Purine ca. 100 unlisted Hazard Symbols: T Risk Phrases: 23/24/25 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Toxic by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. May cause chemical conjunctivitis. Skin: Causes skin irritation. Toxic in contact with skin. Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated. Toxic if swallowed. Inhalation: Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Toxic if inhaled. Can produce delayed pulmonary edema. Chronic: Effects may be delayed. Section 4 - FIRST AID MEASURES Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Ingestion: Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing Media: In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use agent most appropriate to extinguish fire. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Discard contaminated shoes. Storage: Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 5462-86-2: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Not available. Color: Not available. Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: Not available. Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C7H7ClN4 Molecular Weight: 182.61 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable at room temperature in closed containers under normal storage and handling conditions. Conditions to Avoid: Incompatible materials, excess heat. Incompatibilities with Other Materials: Oxidizing agents. Hazardous Decomposition Products: Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide. Hazardous Polymerization: Not available. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 5462-86-2 unlisted. LD50/LC50: Not available. Carcinogenicity: 6-Chloro-9-Ethyl-9H-Purine - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: T Risk Phrases: R 23/24/25 Toxic by inhalation, in contact with skin and if swallowed. R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 24/25 Avoid contact with skin and eyes. S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 5462-86-2: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 5462-86-2 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 5462-86-2 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 海关编码: 2933990090

合成路线

75-03-6 87-42-3 ~49% 5462-86-2

文献：Pharmacia and Upjohn S.p.A. Patent: US5965563 A1, 1999 ;

74-96-4 87-42-3 ~46% 5462-86-2 74972-79-5

文献：Zhang, Qian; Cheng, Gang; Huang, Yong-Zhen; Qu, Gui-Rong; Niu, Hong-Ying; Guo, Hai-Ming Tetrahedron, 2012 , vol. 68, # 38 p. 7822 - 7826

14036-06-7 98140-03-5 ~87% 5462-86-2

文献：Lambertucci, Catia; Antonini, Ippolito; Buccioni, Michela; Dal Ben, Diego; Kachare, Dhuldeo D.; Volpini, Rosaria; Klotz, Karl-Norbert; Cristalli, Gloria Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 7 p. 2812 - 2822

2715-68-6 ~67% 5462-86-2

文献：Nair, Vasu; Richardson, Stephen G. Journal of Organic Chemistry, 1980 , vol. 45, # 20 p. 3969 - 3974

66224-66-6 ~% 5462-86-2

文献：Nair, Vasu; Richardson, Stephen G. Journal of Organic Chemistry, 1980 , vol. 45, # 20 p. 3969 - 3974

64-17-5 87-42-3 ~82% 5462-86-2 74972-79-5

文献：Toyota; Katagiri; Kaneko Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 4 p. 1039 - 1041

上下游产品

上游产品  8
75-03-6 87-42-3 74-96-4 14036-06-7
98140-03-5 2715-68-6 66224-66-6 64-17-5
下游产品  6
25870-60-4 31010-51-2 7252-00-8 5427-22-5
5427-20-3 5427-23-6

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%