5427-20-3

• 常用中文名：6H-Purine-6-thione,9-ethyl-1,9-dihydro-
• 常用英文名：6H-Purine-6-thione,9-ethyl-1,9-dihydro-
• CAS号：5427-20-3
• 分子式：C₇H₈N₄S
• 分子量：180.23000
• 发布时间：2017-12-10 00:13:15
• 更新时间：2024-01-17 06:31:47

名称

• 英文名: 9-ethyl-3H-purine-6-thione
• 英文别名: 9-Ethyl-6-MP; 9-Ethyl-1,9-dihydro-6H-purine-6-thione; 9H-Purine-6-thiol,9-ethyl; 9-Aethyl-1,9-dihydro-purin-6-thion; 9H-Purine-6(1H)-thione,9-ethyl; 9-ETHYL-6-MERCAPTOPURINE; 9-ethyl-1,9-dihydro-purine-6-thione; 9-Ethyl mercaptopurine; 9-Ethyl-9H-purin-6(1H)-thion; 6-thio-9-ethylpurine

物化性质

• 分子式: C₇H₈N₄S
• 分子量: 180.23000
• 精确质量: 180.04700
• PSA: 78.59000
• LogP: 1.50880

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UP0270000 CHEMICAL NAME : 9H-Purine-6-thiol, 9-ethyl- CAS REGISTRY NUMBER : 5427-20-3 BEILSTEIN REFERENCE NO. : 0162062 LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C7-H8-N4-S MOLECULAR WEIGHT : 180.25 WISWESSER LINE NOTATION : T56 BN DN FN HNJ D2 ISH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 400 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ADTEAS Advances in Teratology. (New York, NY) V.1-5, 1966-72. Discontinued. Volume(issue)/page/year: 3,181,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 289 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. (Bethesda, MD 20205) Volume(issue)/page/year: JAN1986 TYPE OF TEST : LD10 - Lethal Dose ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 52 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PMDCAY Progress in Medical Chemistry. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1961- Volume(issue)/page/year: 7,69,1970

安全

• 海关编码: 2933990090

合成路线

98140-03-5 ~% 5427-20-3

文献：Montgomery; Temple Journal of the American Chemical Society, 1957 , vol. 79, p. 5238,5241

5462-86-2 17356-08-0 ~% 5427-20-3

文献：Montgomery; Temple Journal of the American Chemical Society, 1957 , vol. 79, p. 5238,5241

446-86-6 ~% 5427-20-3

文献：Kochergin; Aleksandrova; Korsunskii Chemistry of Heterocyclic Compounds, 2000 , vol. 36, # 3 p. 311 - 318

304441-05-2 ~% 5427-20-3

文献：Kochergin; Aleksandrova; Korsunskii Chemistry of Heterocyclic Compounds, 2000 , vol. 36, # 3 p. 311 - 318

304441-08-5 ~28% 5427-20-3

文献：Kochergin; Aleksandrova; Korsunskii Chemistry of Heterocyclic Compounds, 2000 , vol. 36, # 3 p. 311 - 318

上下游产品

上游产品  5
98140-03-5 5462-86-2 446-86-6 304441-05-2
304441-08-5
下游产品  1
7252-00-8

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%