475561-89-8

• 常用中文名：4-氟-1H-吡咯-2-甲酸甲酯
• 常用英文名：Methyl 4-fluoro-1H-pyrrole-2-carboxylate
• CAS号：475561-89-8
• 分子式：C₆H₆FNO₂
• 分子量：143.116
• 发布时间：2018-10-06 00:25:17
• 更新时间：2024-01-22 23:55:07

名称

• 中文名: 4-氟-1H-吡咯-2-羧酸甲酯
• 英文名: Methyl 4-fluoro-1H-pyrrole-2-carboxylate
• 中文别名: 4-氟吡咯-2-甲酸甲酯; 4-氟-1H-吡咯-2-甲酸甲酯; 甲基4-氟-1H-吡咯-2-羧酸酯
• 英文别名: Methyl 4-fluoro-1H-pyrrole-2-carboxylate; Methyl 4-Fluoropyrrole-2-carboxylate; 1H-Pyrrole-2-carboxylic acid, 4-fluoro-, methyl ester; 4-fluoro-1H-pyrrole-2-carboxylic acid methyl ester; 1H-Pyrrole-2-carboxylicacid,4-fluoro-,methylester(9CI)

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 244.3±25.0 °C at 760 mmHg
• 分子式: C₆H₆FNO₂
• 分子量: 143.116
• 闪点: 101.6±23.2 °C
• 精确质量: 143.038254
• PSA: 42.09000
• LogP: 1.45
• 蒸汽压: 0.0±0.5 mmHg at 25°C
• 折射率: 1.503
• 储存条件: 室温，干燥

合成路线

915230-15-8 ~79% 475561-89-8

文献：ADDEX PHARMACEUTICALS SA Patent: WO2006/123257 A2, 2006 ; Location in patent: Page/Page column 71 ; WO 2006/123257 A2

203866-17-5 ~% 475561-89-8

文献：Leroy, Jacques; Porhiel, Emmanuel; Bondon, Arnaud Tetrahedron, 2002 , vol. 58, # 33 p. 6713 - 6722

114676-69-6 ~% 475561-89-8

文献：BRISTOL-MYERS SQUIBB COMPANY; WROBLESKI, Stephen T.; JAGABANDHU, Das; DOWEYKO, Lidia M.; GUO, Junqing; HYNES, John; JIANG, Bin; KEMPSON, James; LIN, Shuqun; SPERGEL, Steven H.; TOKARSKI, John S.; WU, Hong; YANG, Bingwei Vera Patent: WO2012/125887 A1, 2012 ; WO 2012/125887 A1

256487-77-1 ~% 475561-89-8

文献：BRISTOL-MYERS SQUIBB COMPANY; WROBLESKI, Stephen T.; JAGABANDHU, Das; DOWEYKO, Lidia M.; GUO, Junqing; HYNES, John; JIANG, Bin; KEMPSON, James; LIN, Shuqun; SPERGEL, Steven H.; TOKARSKI, John S.; WU, Hong; YANG, Bingwei Vera Patent: WO2012/125887 A1, 2012 ; WO 2012/125887 A1

647857-74-7 ~% 475561-89-8

文献：BRISTOL-MYERS SQUIBB COMPANY; WROBLESKI, Stephen T.; JAGABANDHU, Das; DOWEYKO, Lidia M.; GUO, Junqing; HYNES, John; JIANG, Bin; KEMPSON, James; LIN, Shuqun; SPERGEL, Steven H.; TOKARSKI, John S.; WU, Hong; YANG, Bingwei Vera Patent: WO2012/125887 A1, 2012 ; WO 2012/125887 A1

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