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309-29-5生产厂家

309-29-5价格

309-29-5

309-29-5结构式
309-29-5结构式
  • 常用中文名:多沙普仑
  • 常用英文名:Doxapram
  • CAS号:309-29-5
  • 分子式:C24H30N2O2
  • 分子量:378.507
  • 相关类别: 原料药 神经系统用药 中枢兴奋药
  • 发布时间:2018-06-29 10:37:06
  • 更新时间:2024-01-08 19:07:51
  • Doxapram能抑制TASK-1,TASK-3和TASK-1/TASK-3异二聚体通道,EC50分别为410 nM,37 μM和9 μM。

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中文名 多沙普仑
英文名 doxapram
中文别名 1-乙基-4-(2-吗啉-4-乙基)-3,3-二苯基-2-吡咯烷酮
吗乙苯吡酮
英文别名 Doxapramum
Dopram
1-Ethyl-4-[2-(4-morpholinyl)ethyl]-3,3-diphenyl-2-pyrrolidinone
1-ethyl-4-(2-morpholin-4-ylethyl)-3,3-diphenylpyrrolidin-2-one
2-Pyrrolidinone, 1-ethyl-4-(2-(4-morpholinyl)ethyl)-3,3-diphenyl-
Doxapram HCL
doxapram
UNII:94F3830Q73
1-ethyl-4-[2-(morpholin-4-yl)ethyl]-3,3-diphenylpyrrolidin-2-one
doxapram hydrochloride
2-Pyrrolidinone, 1-ethyl-4-[2-(4-morpholinyl)ethyl]-3,3-diphenyl-
密度 1.1±0.1 g/cm3
沸点 536.4±50.0 °C at 760 mmHg
分子式 C24H30N2O2
分子量 378.507
闪点 278.2±30.1 °C
精确质量 378.230713
PSA 32.78000
LogP 3.23
外观性状 粉末
蒸汽压 0.0±1.4 mmHg at 25°C
折射率 1.562
储存条件 -20℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UY5769500
CHEMICAL NAME :
2-Pyrrolidinone, 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-
CAS REGISTRY NUMBER :
309-29-5
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C24-H30-N2-O2
MOLECULAR WEIGHT :
378.56
WISWESSER LINE NOTATION :
T6N DOTJ A2- DT5NVTJ A2 CR& CR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
268 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity)
REFERENCE :
JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 30,522,1978 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
DOSE :
1800 ug/kg
SEX/DURATION :
female 16 week(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - other effects to embryo
REFERENCE :
BJOGAS British Journal of Obstetrics and Gynaecology. (Blackwell Scientific Pub. Ltd., POB 88, Oxford, UK) V.82- 1975- Volume(issue)/page/year: 84,48,1977

海关编码 2934999090

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309-29-5结构式

309-29-5

文献:US2013/109689 A1, ; Paragraph 0084 ;
海关编码 2934999090
中文概述 2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素 品名, 成分含量, 用途
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%