33784-05-3

• 常用中文名：7β-螺内酯
• 常用英文名：7β-Spironolactone
• CAS号：33784-05-3
• 分子式：C₂₄H₃₂O₄S
• 分子量：416.573
• 发布时间：2017-06-19 10:29:11
• 更新时间：2026-07-15 12:06:22

名称

• 中文名: 7β-螺内酯
• 英文名: 7β-Spironolactone
• 中文别名: 螺内酯杂质5(螺内酯杂质E); S-((2'R,7S,8R,9S,10R,13S,14S)-10,13-二甲基-3,5'-二氧-1,2,3,4',5',6,7,8,9,10,11,12,13,14,15,16-十六氢-3'H-螺环戊烷[A]菲-17,2'-呋喃]-7-基)乙硫酯 (螺内酯杂质); 7Β,安体舒通; 螺内酯(安体舒通)杂质E; 7BETA-螺内酯; 安体舒通杂质E; 螺内酯杂质E /BP); 7-Β-螺内酯; 螺内酯杂质E; 螺内酯杂质E(7-Β螺内酯)
• 英文别名: 7-Beta-Spironolactone; Spironolactone Impurity E; 17-Hydroxy-7β-Mercapto-3-oxo-17α-pregn-4-ene-21-cboxylic Acid γ-Lactone Acetate; 3'-(3-Oxo-7β-acetylthio-17β-hydroxyandrost-4-en-17α-yl)-propionic Acid Lactone; S-[(7S,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxospiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,2'-oxolane]-7-yl] ethanethioate; S-((2'R,7S,8R,9S,10R,13S,14S)-10,13-Dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-yl) ethanethioate (Spironolactone Impurity); Ethanethioic acid, S-[(7R,8R,10R,13S,17R)-1,2,3,4',5',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-10,13-dimethyl-3,5'-dioxospiro[17H-cyclopenta[a]phenanthrene-17,2'(3'H)-furan]-7-yl] ester; 7β-(Acetylthio)-17α-hydroxy-3-oxopregn-4-ene-21-cboxylic Acid γ-Lactone; S-[(7R,8R,10R,13S,17R)-10,13-Dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-yl] ethanethioate; Spironolactone Impurity E (7-Beta Spironolactone); S-((2'R,7S,8R,9S,10R,13S,14S)-10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-yl) ethanethioate; Spironolactone Impurity 5（Spironolactone Impurity E）; S-[(2′R)-3,5′-dioxo-3′,4′-dihydro-5′H-spiro[androst-4-ene-17,2′-furan]-7β-yl] ethanethioate (7β-spironolactone)

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 597.0±50.0 °C at 760 mmHg
• 分子式: C₂₄H₃₂O₄S
• 分子量: 416.573
• 闪点: 302.3±18.1 °C
• 精确质量: 416.202118
• PSA: 85.74000
• LogP: 3.12
• 蒸汽压: 0.0±1.7 mmHg at 25°C
• 折射率: 1.586

合成路线

976-71-6 507-09-5 ~0% 33784-05-3 52-01-7

文献：Wuts, Peter G. M.; Ritter, Allen R. Journal of Organic Chemistry, 1989 , vol. 54, # 21 p. 5180 - 5182

434-03-7 ~% 33784-05-3

文献：Wuts, Peter G. M.; Ritter, Allen R. Journal of Organic Chemistry, 1989 , vol. 54, # 21 p. 5180 - 5182

50407-76-6 ~% 33784-05-3

文献：Wuts, Peter G. M.; Ritter, Allen R. Journal of Organic Chemistry, 1989 , vol. 54, # 21 p. 5180 - 5182

976-70-5 ~% 33784-05-3

文献：Wuts, Peter G. M.; Ritter, Allen R. Journal of Organic Chemistry, 1989 , vol. 54, # 21 p. 5180 - 5182

121936-43-4 ~% 33784-05-3

文献：Wuts, Peter G. M.; Ritter, Allen R. Journal of Organic Chemistry, 1989 , vol. 54, # 21 p. 5180 - 5182

75219-50-0 ~% 33784-05-3

文献：Wuts, Peter G. M.; Ritter, Allen R. Journal of Organic Chemistry, 1989 , vol. 54, # 21 p. 5180 - 5182

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