CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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HM3950000
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CHEMICAL NAME :
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1H-1,4-Diazepine, hexahydro-1,4-dinitroso-
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CAS REGISTRY NUMBER :
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55557-00-1
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BEILSTEIN REFERENCE NO. :
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0147155
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LAST UPDATED :
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199710
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DATA ITEMS CITED :
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9
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MOLECULAR FORMULA :
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C5-H10-N4-O2
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MOLECULAR WEIGHT :
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158.19
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WISWESSER LINE NOTATION :
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T7N DNTJ ANO DNO
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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65 mg/kg/2Y-I
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TOXIC EFFECTS :
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Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Liver - tumors
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TYPE OF TEST :
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TD - Toxic dose (other than lowest)
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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105 mg/kg/30W-I
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TOXIC EFFECTS :
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Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors
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TYPE OF TEST :
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TD - Toxic dose (other than lowest)
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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1530 mg/kg/31W-I
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TOXIC EFFECTS :
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Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Gastrointestinal - tumors
MUTATION DATA
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TYPE OF TEST :
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Mutation in mammalian somatic cells
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TEST SYSTEM :
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Rodent - hamster Ovary
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DOSE/DURATION :
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5 umol/L
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REFERENCE :
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TCMUE9 Topics in Chemical Mutagenesis. (Plenum Pub. Corp., 233 Spring Street, New York, NY 10013) V.1- 1984- Volume(issue)/page/year: 1,129,1984
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