28957-33-7

• 常用中文名：(R)-3-氨基-2-己内酰胺
• 常用英文名：(R)-3-Amino-2-azepanone
• CAS号：28957-33-7
• 分子式：C₆H₁₂N₂O
• 分子量：128.172
• 发布时间：2018-06-01 08:00:00
• 更新时间：2026-07-10 11:49:34

名称

• 中文名: (R)-3-氨基-2-己内酰胺
• 英文名: (3R)-3-aminoazepan-2-one
• 中文别名: (R)-ALPHA-氨基-OMEGA-己内酰胺; (R)-3-氨基-2-己内酰胺(R)-3-Amino-2-azanone; 氨基高哌啶杂质2; 赖氨酸杂质21; (R)-3-氨基高哌啶-2-酮; (3R)-氮杂环庚烷-3-胺; (R)-3-氨基-氮杂庚烷-2-酮; (R)-3-氨基氮杂环庚烷-2-酮; 3-氨基己内酰胺盐酸盐; (R)-3-氨基-2-氮杂环庚酮; 赖氨酸内酰胺,D
• 英文别名: (3R)-3-aminoazan-2-one; 2H-Azin-2-one, 3-aminohexahydro-, (R); (3R)-3α-Aminohexahydro-1H-azine-2-one; [R,(+)]-3-Aminohexahydro-1H-azin-2-one; (R)-3-Aminohexahydro-1H-azin-2-one; DL-a-Amino-e-caprolactam; 3-Amino-2-azepanone; (±)-α-Amino-ω-caprolactam; D-2-aminohexano-6-lactam; 2H-Azin-2-one, 3-aMinohexahydro-, (3R); Amino homopiperidine impurities2; (3R)-3α-Aminohexahydro-2H-azine-2-one; Lysine lactam, D; (R)-3-Amino-Hexahydro-1H-Azin; Xylose Impurity 6; Lysine Impurity; (+)-α-Amino-ε-caprolactam; 3-Aminoazepan-2-one; (R)-3-Amino-2-azanone; (R)-a-Amino-omega-caprolactam; D-Lysine lactam; (R)-3-AMinoazane; (2R)-2,6-Diaminohexanoic acid 1,6-lactam

物化性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 315.1±35.0 °C at 760 mmHg
• 分子式: C₆H₁₂N₂O
• 分子量: 128.172
• 闪点: 144.4±25.9 °C
• 精确质量: 128.094955
• PSA: 55.12000
• LogP: -1.64
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.470
• 储存条件: 2-8°C

安全

• 危害码 (欧洲): Xi
• 危险品运输编码: UN 1759
• 包装等级: III
• 海关编码: 2933790090

合成路线

108491-55-0 ~% 28957-33-7

文献：ELAN PHARMACEUTICALS, INC. Patent: WO2006/78753 A1, 2006 ; Location in patent: Page/Page column 78 ;

7274-88-6 ~14% 28957-33-7

文献：Galley, Guido; Kitas, Eric Argirios; Jakob-Roetne, Roland Patent: US2006/14945 A1, 2006 ; Location in patent: Page/Page column 41 ;

13515-95-2 ~% 28957-33-7

文献：Stranix, Brent Richard; Sauve, Gilles; Bouzide, Abderrahim; Cote, Alexandre; Berube, Gervais; Soucy, Patrick; Zhao, Yongsen; Yelle, Jocelyn Patent: US2002/151546 A1, 2002 ;

17929-90-7 ~0% 28957-33-7 21568-87-6

文献：Urbanczyk-Lipkowska, Zofia; Fukuda, Noriaki; Tanaka, Koichi Tetrahedron Asymmetry, 2007 , vol. 18, # 10 p. 1254 - 1256

923-27-3 ~95% 28957-33-7

文献：Parker, Michael F.; Bronson, Joanne J.; Barten, Donna M.; Corsa, Jason A.; Du, Wengsheng; Felsenstein, Kevin M.; Guss, Valerie L.; Izzarelli, Darcy; Loo, Alice; McElhone, Kate E.; Marcin, Larry R.; Padmanabha, Ramesh; Pak, Roger; Polson, Craig T.; Toyn, Jeremy H.; Varma, Sam; Wang, Jian; Wong, Victoria; Zheng, Ming; Roberts, Susan B. Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 21 p. 5790 - 5795

372961-87-0 ~% 28957-33-7

文献：Banwell; McRae Journal of Organic Chemistry, 2001 , vol. 66, # 20 p. 6768 - 6774

6804-88-2 ~% 28957-33-7 21568-87-6

文献：Klabunovskii, E. I.; Gogoladze, D. D.; Levitina, E. S.; Karpeiskaya, E. I.; Godunova, L. F.; et al. Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1987 , vol. 36, # 7 p. 1475 - 1478 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1987 , # 7 p. 1597 - 1600

92122-45-7 ~% 28957-33-7

文献：Banwell; McRae Journal of Organic Chemistry, 2001 , vol. 66, # 20 p. 6768 - 6774

17929-90-7 ~% 28957-33-7

文献：Belyaev, Alexander A. Tetrahedron Letters, 1995 , vol. 36, # 3 p. 439 - 440 Title/Abstract Full Text View citing articles Show Details Rezler, Evonne M.; Fenton, Ronald R.; Esdale, Warren J.; McKeage, Mark J.; Russell, Pamela J.; Hambley, Trevor W. Journal of Medicinal Chemistry, 1997 , vol. 40, # 22 p. 3508 - 3515

上下游产品

上游产品  6
108491-55-0 7274-88-6 17929-90-7 923-27-3
6804-88-2 92122-45-7
下游产品  2
106691-72-9 179686-45-4

海关

海关编码	2933790090
中文概述	2933790090 其他内酰胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:9.0% 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%