23518-25-4

• 常用中文名：(+-)-PGF2-alpha
• 常用英文名：(+-)-PGF2-alpha
• CAS号：23518-25-4
• 分子式：C₂₀H₃₄O₅
• 分子量：354.48100
• 发布时间：2017-09-27 16:52:41
• 更新时间：2024-01-27 17:11:41

名称

• 英文名: (5E,13E)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic acid
• 英文别名: 9-oxo-11S,15S-dihydroxy-13E-prostaenoic acid; 11-epi-PGE1; 11-Epiprostaglandin E1

物化性质

• 密度: 1.153g/cm3
• 沸点: 531ºC at 760 mmHg
• 分子式: C₂₀H₃₄O₅
• 分子量: 354.48100
• 闪点: 289ºC
• 精确质量: 354.24100
• PSA: 97.99000
• LogP: 3.04290
• 蒸汽压: 1.71E-13mmHg at 25°C
• 折射率: 1.569

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : MJ9656000 CHEMICAL NAME : 5-Heptenoic acid, 7-(3,5-dihydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl)- , dl- CAS REGISTRY NUMBER : 23518-25-4 LAST UPDATED : 199612 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C20-H34-O5 MOLECULAR WEIGHT : 354.54 WISWESSER LINE NOTATION : L5TJ AQ B2U4VQ C1U1YQ5 DQ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 32 mg/kg SEX/DURATION : female 4-7 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - other measures of fertility REFERENCE : JOENAK Journal of Endocrinology. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1939- Volume(issue)/page/year: 53,201,1972 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 20 mg/kg SEX/DURATION : female 4-7 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) REFERENCE : PRGLBA Prostaglandins. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022) V.1- 1972- Volume(issue)/page/year: 2,375,1972 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 9 mg/kg SEX/DURATION : female 4-6 day(s) after conception TOXIC EFFECTS : Reproductive - Maternal Effects - uterus, cervix, vagina Reproductive - Fertility - other measures of fertility REFERENCE : JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 28,451,1972 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 36 mg/kg SEX/DURATION : female 4-6 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - other measures of fertility REFERENCE : JOENAK Journal of Endocrinology. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1939- Volume(issue)/page/year: 53,201,1972 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 600 ug/kg SEX/DURATION : female 4-6 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) REFERENCE : JOENAK Journal of Endocrinology. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1939- Volume(issue)/page/year: 53,201,1972 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 400 ug/kg SEX/DURATION : female 4 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - other measures of fertility REFERENCE : JOENAK Journal of Endocrinology. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1939- Volume(issue)/page/year: 53,201,1972