CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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MJ5960000
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CHEMICAL NAME :
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3-Heptanone, 6-(dimethylamino)-4,4-diphenyl-, (+-)-
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CAS REGISTRY NUMBER :
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297-88-1
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LAST UPDATED :
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199806
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DATA ITEMS CITED :
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8
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MOLECULAR FORMULA :
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C21-H27-N-O
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MOLECULAR WEIGHT :
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309.49
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WISWESSER LINE NOTATION :
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2VXR&R&1Y1&N1&1 -(+-)
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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95 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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28 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Subcutaneous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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28 mg/kg
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TOXIC EFFECTS :
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Behavioral - convulsions or effect on seizure threshold Behavioral - excitement Lungs, Thorax, or Respiration - respiratory depression
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Mammal - dog
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DOSE/DURATION :
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26 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Intraperitoneal
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DOSE :
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240 mg/kg
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SEX/DURATION :
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female 7 day(s) pre-mating - 21 day(s) post-birth
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TOXIC EFFECTS :
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Reproductive - Effects on Newborn - other neonatal measures or effects Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) Reproductive - Effects on Newborn - behavioral
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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DOSE :
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12500 ug/kg
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SEX/DURATION :
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lactating female 5 day(s) post-birth
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TOXIC EFFECTS :
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Reproductive - Effects on Newborn - biochemical and metabolic
MUTATION DATA
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TYPE OF TEST :
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Mutation test systems - not otherwise specified
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TEST SYSTEM :
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Rodent - rat Testis
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DOSE/DURATION :
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10 umol/L
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REFERENCE :
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BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 27,123,1978
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