89450-91-9

• 常用中文名：2-[(2-anilinopyrimidin-4-yl)amino]benzoic acid
• 常用英文名：2-[(2-anilinopyrimidin-4-yl)amino]benzoic acid
• CAS号：89450-91-9
• 分子式：C₁₇H₁₄N₄O₂
• 分子量：306.31900
• 发布时间：2016-06-11 07:08:45
• 更新时间：2024-04-05 17:09:16

名称

• 英文名: 2-[(2-anilinopyrimidin-4-yl)amino]benzoic acid
• 英文别名: 2-{[2-(phenylamino)pyrimidin-4-yl]amino}benzoic acid; Benzoic acid,2-((2-(phenylamino)-4-pyrimidinyl)amino); N-(2-(PHENYLAMINO)-PYRIMIDIN-4-YL)ANTHRANILIC ACID; N4-(2-carboxyphenyl)-N2-(phenyl)pyrimidine-2,4-diamine; ANTHRANILIC ACID,N-(2-ANILINO-4-PYRIMIDINYL); 2-Phenylamino-4-(o-carboxyphenylamino)pyrimidine; N-(2-Anilino-4-pyrimidinyl)anthranilic acid

物化性质

• 密度: 1.389g/cm3
• 沸点: 561.3ºC at 760 mmHg
• 分子式: C₁₇H₁₄N₄O₂
• 分子量: 306.31900
• 闪点: 293.2ºC
• 精确质量: 306.11200
• PSA: 90.37000
• LogP: 3.15690
• 折射率: 1.731

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : CB2541000 CHEMICAL NAME : Anthranilic acid, N-(2-anilino-4-pyrimidinyl)- CAS REGISTRY NUMBER : 89450-91-9 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C17-H14-N4-O2 MOLECULAR WEIGHT : 306.35 WISWESSER LINE NOTATION : T6N CNJ BMR& DMR BVQ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1130 mg/kg TOXIC EFFECTS : Behavioral - analgesia REFERENCE : RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 47,18,1984

合成路线

74497-02-2 31185-80-5 ~79% 89450-91-9

文献：Karn, V. K.; Tat'yanchenko, I. S.; Portnyagina, V. A.; Mokhort, N. A.; Ryabukha, T. K.; Vinnikova, A. V. Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 11 p. 777 - 779 Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 11 p. 1304 - 1307

118-92-3 ~% 89450-91-9

文献：Liu, Mei; Wang, Sanyi; Clampit, Jill E.; Gum, Rebecca J.; Haasch, Deanna L.; Rondinone, Cristina M.; Trevillyan, James M.; Abad-Zapatero, Cele; Fry, Elizabeth H.; Sham, Hing L.; Liu, Gang Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 3 p. 668 - 672