10541-69-2

• 常用中文名：2,5-二氯苄胺
• 常用英文名：1-(3,5-Dichlorophenyl)methanamine
• CAS号：10541-69-2
• 分子式：C₇H₇Cl₂N
• 分子量：176.043
• 发布时间：2018-09-15 21:12:26
• 更新时间：2024-01-09 12:00:37

名称

• 中文名: 2,5-二氯苄胺
• 英文名: 2,5-Dichlorobenzylamine
• 中文别名: 2,5-二氯苯甲胺
• 英文别名: 2,5-DICHLOROBENZYLAMINE; Benzenemethanamine, 2,5-dichloro-; 2,5-DichlorobenzeneMethanamine; 2,5-dichloro-benzyl amine; 2,5-dichloro-N-methyl-aniline; (2,5-dichlorophenyl)methanamine; 1-(2,5-Dichlorophenyl)methanamine; 2,5-Dichloro-benzylamine; 2 5-DICHLOROBENZYLAMINE; 2,5-Dichlorobenzylam; 2,4-DIETHYL-2,6-HEPTADIENAL; MFCD00052391; (2,5-dichlorophenyl)methylamine; 2,5-Dichlor-N-methyl-anilin; 1-(3,5-Dichlorophenyl)methanamine; Benzenemethanamine, 3,5-dichloro-; 2,5-Dichlor-benzylamine

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 248.8±25.0 °C at 760 mmHg
• 分子式: C₇H₇Cl₂N
• 分子量: 176.043
• 闪点: 104.2±23.2 °C
• 精确质量: 174.995560
• PSA: 26.02000
• LogP: 2.21
• 蒸汽压: 0.0±0.5 mmHg at 25°C
• 折射率: 1.582
• 储存条件:

  储存在干爽的惰性气体下，置于阴凉处。

• 稳定性:

  遵照规格使用和储存则不会分解。

• 分子结构:

  1、 摩尔折射率：44.49

  2、 摩尔体积（cm³/mol）：133.3

  3、 等张比容（90.2K）：344.8

  4、 表面张力（dyne/cm）：44.7

  5、 极化率（10^-24cm³）：17.63

• 计算化学:

  1、 疏水参数计算参考值（XlogP）：2

  2、 氢键供体数量：1

  3、 氢键受体数量：1

  4、 可旋转化学键数量：1

  5、 拓扑分子极性表面积（TPSA）：26

  6、 重原子数量：10

  7、 表面电荷：0

  8、 复杂度：108

  9、 同位素原子数量：0

  10、 确定原子立构中心数量：0

  11、 不确定原子立构中心数量：0

  12、 确定化学键立构中心数量：0

  13、 不确定化学键立构中心数量：0

  14、 共价键单元数量：1

• 更多:

  1. 性状：无色至黄色液体

  2. 密度（g/mL,25/4℃）： 1.318

  3. 相对蒸汽密度（g/mL,空气=1）：无可用

  4. 熔点（ºC）：无可用

  5. 沸点（ºC,常压）：74-76（0.1mmHg）

  6. 沸点（ºC,5.2kPa）： 无可用

  7. 折射率： 无可用

  8. 闪点（ºC）： >110

  9. 比旋光度（º）：无可用

  10. 自燃点或引燃温度（ºC）：无可用

  11. 蒸气压（kPa,25ºC）：无可用

  12. 饱和蒸气压（kPa,60ºC）：无可用

  13. 燃烧热（KJ/mol）：无可用

  14. 临界温度（ºC）：无可用

  15. 临界压力（KPa）：无可用

  16. 油水（辛醇/水）分配系数的对数值：无可用

  17. 爆炸上限（%,V/V）：无可用

  18. 爆炸下限（%,V/V）： 无可用

  19. 溶解性：难溶于水

MSDS

Name: 2 5-Dichlorobenzylamine 97% Material Safety Data Sheet Synonym: CAS: 10541-69-2 Section 1 - Chemical Product MSDS Name:2 5-Dichlorobenzylamine 97% Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 10541-69-2 2,5-Dichlorobenzylamine 97% unlisted Hazard Symbols: C Risk Phrases: 34 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Causes burns.Moisture sensitive. Potential Health Effects Eye: Causes eye burns. Skin: Causes skin burns. Ingestion: Causes gastrointestinal tract burns. Inhalation: Causes chemical burns to the respiratory tract. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Do not induce vomiting. Get medical aid immediately. Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use foam, dry chemical, or carbon dioxide. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Section 7 - HANDLING and STORAGE Handling: Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood. Storage: Store in a cool, dry place. Store in a tightly closed container. Corrosives area. Store under an inert atmosphere. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 10541-69-2: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Liquid Color: pale yellow Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: 74 - 77 deg C @0.1mmHg Freezing/Melting Point: Not available. Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C7H7Cl2N Molecular Weight: 176 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials, exposure to moist air or water. Incompatibilities with Other Materials: Oxidizing agents, acids, acid chlorides. Hazardous Decomposition Products: Hydrogen chloride, chlorine, nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 10541-69-2 unlisted. LD50/LC50: Not available. Carcinogenicity: 2,5-Dichlorobenzylamine - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: AMINES, LIQUID, CORROSIVE, N.O.S.* Hazard Class: 8 UN Number: 2735 Packing Group: III IMO Shipping Name: AMINES, LIQUID, CORROSIVE, N.O.S. Hazard Class: 8 UN Number: 2735 Packing Group: III RID/ADR Shipping Name: AMINES, LIQUID, CORROSIVE, N.O.S. Hazard Class: 8 UN Number: 2735 Packing group: III Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: C Risk Phrases: R 34 Causes burns. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 10541-69-2: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 10541-69-2 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 10541-69-2 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

生态学数据: 通常对水是不危害的，若无政府许可，勿将材料排入周围环境。

安全

• 危害码 (欧洲): C:Corrosive;
• 风险声明 (欧洲): R34
• 安全声明 (欧洲): S26-S36/37/39-S45
• 危险品运输编码: UN 2922
• WGK德国: 3
• 包装等级: III
• 海关编码: 2921499090

合成路线

80959-18-8 ~% 10541-69-2

文献：Journal of Medicinal Chemistry, , vol. 27, # 9 p. 1111 - 1118

793695-86-0 ~% 10541-69-2

文献：Journal of Medicinal Chemistry, , vol. 48, # 6 p. 1745 - 1758

85482-13-9 ~% 10541-69-2

文献：Journal of Medicinal Chemistry, , vol. 48, # 6 p. 1745 - 1758

19398-61-9 ~% 10541-69-2

文献：Journal of the Chemical Society, , p. 1414 - 1416

6361-23-5 540-69-2 ~% 10541-69-2

文献：Journal of the Karnatak University, , vol. 2, p. 19,26

上下游产品

上游产品  6
80959-18-8 793695-86-0 85482-13-9 19398-61-9
6361-23-5 540-69-2
下游产品  0

海关

海关编码	2921499090
中文概述	2921499090 其他芳香单胺及衍生物及它们的盐. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%