538343-04-3

• 常用中文名：4-羟基-8-甲氧基-2-萘羧酸乙酯
• 常用英文名：Ethyl 4-hydroxy-8-methoxy-2-naphthoate
• CAS号：538343-04-3
• 分子式：C₁₄H₁₄O₄
• 分子量：246.25900
• 发布时间：2018-12-25 19:29:51
• 更新时间：2025-09-12 09:40:46

名称

• 中文名: 4-羟基-8-甲氧基-2-萘羧酸乙酯
• 英文名: Ethyl 4-hydroxy-8-methoxy-2-naphthoate
• 英文别名: 4-hydroxy-8-trifluoromethyl-quinoline-3-carboxylic acid ethyl ester; ethyl 8-methoxy-4-hydroxynaphthalene-2-carboxylate; ethyl 4-hydroxy-8-trifluoromethylquinoline-3-carboxylate; ethyl 4-hydroxy-8-methoxy-naphthalene-2-carboxylate; 3-Carbethoxy-4-hydroxy-8-trifluormethyl-chinolin

物化性质

• 密度: 1.228g/cm3
• 沸点: 435.9ºC at 760 mmHg
• 分子式: C₁₄H₁₄O₄
• 分子量: 246.25900
• 闪点: 167ºC
• 精确质量: 246.08900
• PSA: 55.76000
• LogP: 2.73070
• 折射率: 1.605

合成路线

135-02-4 123-25-1 ~% 538343-04-3

文献：MERCK SHARP and DOHME CORP.; DUFFY, Joseph, L.; BAO, Jianming; ONDEYKA, Debra, L.; TYAGARAJAN, Sriram; SHAO, Patrick; YE, Feng; KATIPALLY, Revathi; ZWICKER, Aaron; SHERER, Edward, C.; PLOTKIN, Michael A.; MONINGKA, Remond; HUSSIAN, Zahid; WOOD, Harold B.; UJJAINWALLA, Feroze; ROMERO, Anthony; FINKE, Paul; ZANG, Yi; LIU, Weiguo Patent: WO2012/24183 A1, 2012 ; Location in patent: Page/Page column 159-160 ; WO 2012/024183 A1

33295-50-0 ~53% 538343-04-3

文献：Gabbutt, Christopher D.; Hepworth, John D.; Heron, B. Mark; Thomas, David A.; Kilner, Colin; Partington, Steven M. Heterocycles, 2004 , vol. 63, # 3 p. 567 - 582

135-02-4 ~% 538343-04-3

文献：Gabbutt, Christopher D.; Hepworth, John D.; Heron, B. Mark; Thomas, David A.; Kilner, Colin; Partington, Steven M. Heterocycles, 2004 , vol. 63, # 3 p. 567 - 582

151502-63-5 ~% 538343-04-3

文献：Gabbutt, Christopher D.; Hepworth, John D.; Heron, B. Mark; Thomas, David A.; Kilner, Colin; Partington, Steven M. Heterocycles, 2004 , vol. 63, # 3 p. 567 - 582

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