54649-02-4

• 常用中文名：4-(4-methoxyphenyl)-3-[(2-methyl-1H-indol-3-yl)methyl]-1H-1,2,4-triazole-5-thione
• 常用英文名：4-(4-methoxyphenyl)-3-[(2-methyl-1H-indol-3-yl)methyl]-1H-1,2,4-triazole-5-thione
• CAS号：54649-02-4
• 分子式：C₁₉H₁₈N₄OS
• 分子量：350.43700
• 发布时间：2017-12-12 09:01:50
• 更新时间：2024-01-11 13:38:23

名称

• 英文名: 4-(4-methoxyphenyl)-3-[(2-methyl-1H-indol-3-yl)methyl]-1H-1,2,4-triazole-5-thione

物化性质

• 密度: 1.33g/cm3
• 沸点: 556.7ºC at 760 mmHg
• 分子式: C₁₉H₁₈N₄OS
• 分子量: 350.43700
• 闪点: 290.5ºC
• 精确质量: 350.12000
• PSA: 94.53000
• LogP: 3.94510
• 折射率: 1.698

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : XZ5359120 CHEMICAL NAME : 3H-1,2,4-Triazole-3-thione, 2,4-dihydro-4-(4-methoxyphenyl)-5-((2-methyl-1H-indol -3-yl) methyl)- CAS REGISTRY NUMBER : 54649-02-4 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C19-H18-N4-O-S MOLECULAR WEIGHT : 350.47 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 450 mg/kg TOXIC EFFECTS : Behavioral - altered sleep time (including change in righting reflex) Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression REFERENCE : CNJPAZ Canadian Journal of Pharmaceutical Sciences. (Toronto, Ont., Canada) V.1-16, 1966-81. Discontinued. Volume(issue)/page/year: 9,108,1974

合成路线

54686-44-1 ~75% 54649-02-4

文献：Kadry; Badawy; Hanna Pharmazie, 1986 , vol. 41, # 8 p. 558 - 559

21909-51-3 ~% 54649-02-4

文献：Kadry; Badawy; Hanna Pharmazie, 1986 , vol. 41, # 8 p. 558 - 559

2284-20-0 ~% 54649-02-4

文献：Kadry; Badawy; Hanna Pharmazie, 1986 , vol. 41, # 8 p. 558 - 559