54649-02-4

54649-02-4 structure
54649-02-4 structure

Name 4-(4-methoxyphenyl)-3-[(2-methyl-1H-indol-3-yl)methyl]-1H-1,2,4-triazole-5-thione
Density 1.33g/cm3
Boiling Point 556.7ºC at 760 mmHg
Molecular Formula C19H18N4OS
Molecular Weight 350.43700
Flash Point 290.5ºC
Exact Mass 350.12000
PSA 94.53000
LogP 3.94510
Index of Refraction 1.698

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XZ5359120
CHEMICAL NAME :
3H-1,2,4-Triazole-3-thione, 2,4-dihydro-4-(4-methoxyphenyl)-5-((2-methyl-1H-indol -3-yl) methyl)-
CAS REGISTRY NUMBER :
54649-02-4
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C19-H18-N4-O-S
MOLECULAR WEIGHT :
350.47

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
450 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
CNJPAZ Canadian Journal of Pharmaceutical Sciences. (Toronto, Ont., Canada) V.1-16, 1966-81. Discontinued. Volume(issue)/page/year: 9,108,1974

~75%

54649-02-4 structure

54649-02-4

Literature: Kadry; Badawy; Hanna Pharmazie, 1986 , vol. 41, # 8 p. 558 - 559

~%

54649-02-4 structure

54649-02-4

Literature: Kadry; Badawy; Hanna Pharmazie, 1986 , vol. 41, # 8 p. 558 - 559

~%

54649-02-4 structure

54649-02-4

Literature: Kadry; Badawy; Hanna Pharmazie, 1986 , vol. 41, # 8 p. 558 - 559