176308-97-7

• 常用中文名：4-溴-2-甲基-5-(甲基磺酰基)苯甲酸甲酯
• 常用英文名：methyl 4-bromo-2-methyl-5-methylsulfonylbenzoate
• CAS号：176308-97-7
• 分子式：C₁₀H₁₁BrO₄S
• 分子量：307.16100
• 发布时间：2018-10-20 17:32:53
• 更新时间：2024-01-09 20:02:41

名称

• 中文名: 4-溴-2-甲基-5-(甲基磺酰基)苯甲酸甲酯
• 英文名: methyl 4-bromo-2-methyl-5-methylsulfonylbenzoate
• 英文别名: methyl 4-bromo-5-methanesulfonyl-2-methylbenzoate; methyl 4-bromo-5-methylsulfonyl-2-methylbenzoate; methyl 2-methyl-4-bromo-5-methylsulfonylbenzoate; 4-bromo-5-methanesulfonyl-2-methyl-benzoic acid methyl ester; methyl 2-methyl-4-bromo-5-methylsulphonylbenzoate

物化性质

• 分子式: C₁₀H₁₁BrO₄S
• 分子量: 307.16100
• 精确质量: 305.95600
• PSA: 68.82000
• LogP: 3.02840

合成路线

67-56-1 176309-05-0 ~85% 176308-97-7

文献：BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG; BENTZIEN, Joerg, Martin; BOYER, Stephen, James; BURKE, Jennifer; ELDRUP, Anne, Bettina; GUO, Xin; HUBER, John, David; KIRRANE, Thomas, Martin; SOLEYMANZADEH, Fariba; SWINAMER, Alan, David Patent: WO2010/5783 A1, 2010 ; Location in patent: Page/Page column 95 ; WO 2010/005783 A1

75-36-5 176309-05-0 ~89% 176308-97-7

文献：Huber, John D.; Bentzien, Joerg; Boyer, Stephen J.; Burke, Jennifer; De Lombaert, Stephane; Eickmeier, Christian; Guo, Xin; Haist, James V.; Hickey, Eugene R.; Kaplita, Paul; Karmazyn, Morris; Kemper, Raymond; Kennedy, Charles A.; Kirrane, Thomas; Madwed, Jeffrey B.; Mainolfi, Elizabeth; Nagaraja, Nelamangara; Soleymanzadeh, Fariba; Swinamer, Alan; Eldrup, Anne B. Journal of Medicinal Chemistry, 2012 , vol. 55, # 16 p. 7114 - 7140

68837-59-2 ~% 176308-97-7

文献：Huber, John D.; Bentzien, Joerg; Boyer, Stephen J.; Burke, Jennifer; De Lombaert, Stephane; Eickmeier, Christian; Guo, Xin; Haist, James V.; Hickey, Eugene R.; Kaplita, Paul; Karmazyn, Morris; Kemper, Raymond; Kennedy, Charles A.; Kirrane, Thomas; Madwed, Jeffrey B.; Mainolfi, Elizabeth; Nagaraja, Nelamangara; Soleymanzadeh, Fariba; Swinamer, Alan; Eldrup, Anne B. Journal of Medicinal Chemistry, 2012 , vol. 55, # 16 p. 7114 - 7140

176309-02-7 ~% 176308-97-7

文献：Baumgarth, Manfred; Beier, Norbert; Gericke, Rolf Journal of Medicinal Chemistry, 1997 , vol. 40, # 13 p. 2017 - 2034

213120-96-8 74-88-4 ~% 176308-97-7

文献：Baumgarth, Manfred; Beier, Norbert; Gericke, Rolf Journal of Medicinal Chemistry, 1997 , vol. 40, # 13 p. 2017 - 2034