511-09-1

• 常用中文名：麦角克碱
• 常用英文名：alpha-ergocryptine
• CAS号：511-09-1
• 分子式：C₃₂H₄₁N₅O₅
• 分子量：575.698
• 发布时间：2018-02-09 08:00:00
• 更新时间：2026-10-16 11:53:17

名称

• 中文名: 麦角克碱
• 英文名: α-ergocryptine
• 中文别名: 溴隐亭杂质2(溴隐亭MESYLATE杂质B); 麦角隐亭碱; 麥角克普汀; 麦角环肽; 麦角卡里碱; 溴隐亭杂质B; alpha-麦角隐亭; Α-麦角隐亭; 麥角隱亭鹼; 甲磺酸溴隐亭B; 麦角隐亭|Ergocryptine; 甲磺酸溴隐亭杂质B; Α-麦角隐亭 / 甲磺酸溴隐亭杂质B; 爱谷克列斯汀碱; ɑ-麦角隐亭; 麦角脊亭; 麦角克碱/干态标准品
• 英文别名: Cilnidipine Impurity 16; Ergocryptine; 12'-hydroxy-5'; Bromocriptine mesilate Impurity B; Bromocryptine Impurity B (α-Ergocryptine); A-ERGOCRYPTINE ERGOT ALKALOID; (6,9R)-N-[(2R,5S,10aS,10bS)-10b-hydroxy-2-(1-methylethyl)-5-(2-methylpropyl)-3,6-dioxooctahydro-8H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl]-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-cboxamide (α-ergocryptine); (R)-9,10-Dihydro-β 12'-Hydroxy-2'-(1-methylethyl)-5'-α-(2-methylpropyl)ergotaman-3',6',18-trione; alpha-ergokryptine; Bromocriptine Impurity B; (6,9R)-N-((2R,5S,10aS,10bS)-10b-hydroxy-5-isobutyl-2-isopropyl-3,6-dioxooctahydro-2H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-cboxamide; (6aR,9R)-N-[(2R,5S,10aS,10bS)-10b-Hydroxy-5-isobutyl-2-isopropyl-3,6-dioxooctahydro-8H-[1,3]oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl]-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide; Ergocryptine Ergokryptine; ergokryptine; ergocryptine; (5'a)-12'-Hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)ergotaman-3',6',18-trione; ALPHA-ERGOCRYPTINE; 12μ-Hydroxy-2μ-(1-methylethyl)-5μ-α-(2-methylpropyl)ergotaman-3μ,6μ,18-trione; 12'-hydroxy-5'α-isobutyl-2'-isopropylergotaman-3',6',18-trione; (5'α)-12'-Hydroxy-5'-isobutyl-2'-isopropyl-3',6',18-trioxoergotaman; A-ergocryptine; α-Ergocryptine; a-Ergocryptine; Ergotaman-3',6',18-trione, 12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-, (5'α); Ergocrypyine; ErgotaMan-3',6',18-trione,12'-hydroxy-2'-(1-Methylethyl)-5'-(2-Methylpropyl)-, (5'a); Ergocriptine; 12'-Hydroxy-5'α-isobutyl-2'-isopropylergotaman-3',6',18-trione; Bromocriptine Impurity 2（Bromocriptine Mesylate Impurity B); 12'-hydroxy-5'alpha-isobutyl-2'-isopropylergotaman-3',6',18-trione; 12'-Hydroxy-2'-isopropyl-5'α-isobutylergotaman-3',6',18-trione; 12’-hydroxy-2’-(1-methylethyl)-5’-alpha-(2-methylpropyl)ergotaman-3’,6’,18-t; ALPHA-ERGOCRYPTINE //BP; (5'α)-12'-hydroxy-5'-(2-methylpropyl)-3',6',18-trioxo-2'-(propan-2-yl)ergotaman; 4-25-00-00964; 9,10-Dihydro-&beta

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 861.7±65.0 °C at 760 mmHg
• 熔点: 152-154ºC
• 分子式: C₃₂H₄₁N₅O₅
• 分子量: 575.698
• 闪点: 475.0±34.3 °C
• 精确质量: 575.310791
• PSA: 118.21000
• LogP: 4.08
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.681

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : KE1400000 CHEMICAL NAME : Ergocryptine CAS REGISTRY NUMBER : 511-09-1 BEILSTEIN REFERENCE NO. : 0078810 LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C32-H41-N5-O5 MOLECULAR WEIGHT : 575.78 WISWESSER LINE NOTATION : T C6656 1A P GN LM CUTT&&J G1 EVM- DT B565 CO EVN HVNTJ BQ DY1&1 G1Y1&1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 950 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3752814 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 2 mg/kg SEX/DURATION : female 4 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - other measures of fertility Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) REFERENCE : JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 56,691,1979 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 1800 ug/kg SEX/DURATION : lactating female 3 day(s) post-birth TOXIC EFFECTS : Reproductive - Maternal Effects - postpartum REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3752814

安全

• 危害码 (欧洲): Xn
• 风险声明 (欧洲): 62
• 危险品运输编码: UN 1544 6.1/PG 3
• WGK德国: 3
• 包装等级: III
• 危险类别: 6.1(b)

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