75775-64-3

• 常用中文名：ACRIDINE, 9-(3-PYRIDYLAMINO)-
• 常用英文名：ACRIDINE, 9-(3-PYRIDYLAMINO)-
• CAS号：75775-64-3
• 分子式：C₁₈H₁₃N₃
• 分子量：271.31600
• 发布时间：2016-05-01 09:05:51
• 更新时间：2024-02-19 19:53:06

名称

• 英文名: N-pyridin-3-ylacridin-9-amine
• 英文别名: 9-(PYRIDIN-3-YLAMINO)ACRIDINE; acridin-9-yl-pyridin-3-yl-amine; 9-(3-Pyridylamino)acridine; ACRIDINE,9-(3-PYRIDYLAMINO); 9-(3-Pyridylamino)acridin

物化性质

• 密度: 1.291g/cm3
• 沸点: 462.7ºC at 760mmHg
• 分子式: C₁₈H₁₃N₃
• 分子量: 271.31600
• 闪点: 233.7ºC
• 精确质量: 271.11100
• PSA: 37.81000
• LogP: 4.59960

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : AR9486650 CHEMICAL NAME : Acridine, 9-(3-pyridylamino)- CAS REGISTRY NUMBER : 75775-64-3 BEILSTEIN REFERENCE NO. : 0409914 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C18-H13-N3 MOLECULAR WEIGHT : 271.34 WISWESSER LINE NOTATION : T C666 BNJ IM- CT6NJ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD10 - Lethal Dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >500 mg/kg TOXIC EFFECTS : Tumorigenic - active as anti-cancer agent MUTATION DATA TYPE OF TEST : DNA damage TEST SYSTEM : Mammal - species unspecified Lymphocyte DOSE/DURATION : 13 umol/L REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,170,1981

合成路线

1207-69-8 ~% 75775-64-3

文献：SIRTRIS PHARMACEUTICALS, INC. Patent: WO2006/94237 A2, 2006 ; Location in patent: Page/Page column 142 ; WO 2006/094237 A2

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