CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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VN2265000
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CHEMICAL NAME :
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Saframycin A
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CAS REGISTRY NUMBER :
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66082-27-7
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LAST UPDATED :
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199403
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DATA ITEMS CITED :
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3
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MOLECULAR FORMULA :
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C29-H30-N4-O8
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MOLECULAR WEIGHT :
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562.63
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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4900 ug/kg
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TOXIC EFFECTS :
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Tumorigenic - active as anti-cancer agent
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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3300 ug/kg
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TOXIC EFFECTS :
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Tumorigenic - active as anti-cancer agent
MUTATION DATA
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TYPE OF TEST :
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Cytogenetic analysis
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TEST SYSTEM :
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Rodent - hamster Lung
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DOSE/DURATION :
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160 ug/L
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REFERENCE :
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GMCRDC Gann Monograph on Cancer Research. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No. 11- 1971- Volume(issue)/page/year: 27,95,1981
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