58537-99-8

• 常用中文名：4-羟基-2,6-二甲基苯甲腈
• 常用英文名：4-Cyano-3,5-dimethylphenol
• CAS号：58537-99-8
• 分子式：C₉H₉NO
• 分子量：147.174
• 相关类别： 化学试剂 有机试剂 氰化物/腈
• 发布时间：2018-07-16 17:50:14
• 更新时间：2024-01-08 21:17:07
• 下载msds

名称

• 中文名: 4-羟基-2,6-二甲基苯腈
• 英文名: 4-Hydroxy-2,6-dimethylbenzonitrile
• 中文别名: 2,6-二甲基-4-羟基苯腈; 4-羟基-2,6-二甲基苯甲腈
• 英文别名: 4-Hydroxy-2,6-dimethylbenzonitrile; 2,6-dimethyl-4-hydroxy-benzonitrile; Benzonitrile, 4-hydroxy-2,6-dimethyl-; 4-Cyano-3,5-dimethylphenol; MFCD00238591; 2,6-Dimethyl-4-hydroxybenzonitrile

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 313.7±30.0 °C at 760 mmHg
• 熔点: 176ºC
• 分子式: C₉H₉NO
• 分子量: 147.174
• 闪点: 143.5±24.6 °C
• 精确质量: 147.068420
• PSA: 44.02000
• LogP: 2.52
• 外观性状: 灰白色固体
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.564
• 储存条件: 室温，干燥

MSDS

Name: 4-Hydroxy-2 6-dimethylbenzonitrile 97% Material Safety Data Sheet Synonym: 2,6-Dimethyl-4-hydroxybenzonitril CAS: 58537-99-8 Section 1 - Chemical Product MSDS Name:4-Hydroxy-2 6-dimethylbenzonitrile 97% Material Safety Data Sheet Synonym:2,6-Dimethyl-4-hydroxybenzonitril Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 58537-99-8 4-Hydroxy-2,6-dimethylbenzonitrile 97% unlisted Hazard Symbols: XN Risk Phrases: 20/21/22 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Harmful by inhalation, in contact with skin and if swallowed. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. Harmful if absorbed through the skin. Ingestion: Harmful if swallowed. May cause irritation of the digestive tract. Inhalation: Harmful if inhaled. May cause respiratory tract irritation. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 58537-99-8: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: off-white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 169 - 173 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C9H9NO Molecular Weight: 147 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents, acids, bases. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 58537-99-8 unlisted. LD50/LC50: Not available. Carcinogenicity: 4-Hydroxy-2,6-dimethylbenzonitrile - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: NITRILES, SOLID, TOXIC, N.O.S.* Hazard Class: 6.1 UN Number: 3276 Packing Group: III IMO Shipping Name: NITRILES, TOXIC, N.O.S. Hazard Class: 6.1 UN Number: 3276 Packing Group: III RID/ADR Shipping Name: NITRILES, TOXIC, N.O.S. Hazard Class: 6.1 UN Number: 3276 Packing group: III Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. Safety Phrases: S 36/37 Wear suitable protective clothing and gloves. WGK (Water Danger/Protection) CAS# 58537-99-8: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 58537-99-8 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 58537-99-8 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xn: Harmful;
• 风险声明 (欧洲): R20/21/22
• 安全声明 (欧洲): S26
• 危险品运输编码: UN 3276
• 海关编码: 2926909090

合成路线

7463-51-6 557-21-1 ~61% 58537-99-8

文献：Ramnauth, Jailall; Bhardwaj, Namrta; Renton, Paul; Rakhit, Suman; Maddaford, Shawn P. Synlett, 2003 , # 14 p. 2237 - 2239

1004-36-0 105-56-6 ~46% 58537-99-8

文献：Marshall, Laura J.; Cable, Karl M.; Botting, Nigel P. Journal of Labelled Compounds and Radiopharmaceuticals, 2010 , vol. 53, # 5-6 p. 457 - 459

854854-57-2 ~% 58537-99-8

文献：Fortsch. Ch. Phys., vol. 18, p. Heft 2, S. 23

7677-24-9 527-61-7 ~% 4198-90-7 58537-99-8

文献：Tetrahedron Letters, , vol. 35, # 43 p. 7901 - 7904

海关

海关编码	2926909090
中文概述	2926909090 其他腈基化合物. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%