51776-71-7

• 常用中文名：1-溴-4-(二氟甲基)苯
• 常用英文名：1-Bromo-4-(difluoromethyl)benzene
• CAS号：51776-71-7
• 分子式：C₇H₅BrF₂
• 分子量：207.015
• 相关类别： 有机原料 烃类化合物及其衍生物 烃类卤化物
• 发布时间：2018-09-03 22:12:31
• 更新时间：2024-01-02 15:55:10
• 下载msds

名称

• 中文名: 4-溴-α,α-二氟甲苯
• 英文名: 1-Bromo-4-(difluoromethyl)benzene
• 中文别名: 1-溴-4-(二氟甲基)苯
• 英文别名: Benzene, 1-bromo-4-(difluoromethyl)-; 1-Bromo-4-(difluoromethyl)benzene

物化性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 208.4±30.0 °C at 760 mmHg
• 分子式: C₇H₅BrF₂
• 分子量: 207.015
• 闪点: 79.8±24.6 °C
• 精确质量: 205.954269
• LogP: 3.36
• 外观性状: Liquid | Clear colorless to pale yellow
• 蒸汽压: 0.3±0.4 mmHg at 25°C
• 折射率: 1.499
• 储存条件: 室温

MSDS

Material Safety Data Sheet Section1. Identification of the substance Product Name: 1-Bromo-4-(difluoromethyl)benzene Synonyms: Section2. Hazards identification Harmful by inhalation, in contact with skin, and if swallowed. H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H227:Combustible liquid Keep away from heat/sparks/open flames/hot surfaces. No smoking P210: P261:Avoid breathing dust/fume/gas/mist/vapours/spray P280:Wear protective gloves/protective clothing/eye protection/face protection P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing P405:Store locked up Section3. Composition/information on ingredients. Ingredient name:1-Bromo-4-(difluoromethyl)benzene CAS number:51776-71-7 Section4. First aid measures Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing contaminated clothing and shoes. If irritation persists, seek medical attention. Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical attention. Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention. Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention. Section5. Fire fighting measures In the event of a fire involving this material, alone or in combination with other materials, use dry powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus should be worn. Section6. Accidental release measures Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national standards. Respiratory precaution:Wear approved mask/respirator Hand precaution:Wear suitable gloves/gauntlets Skin protection:Wear suitable protective clothing Eye protection:Wear suitable eye protection Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container for disposal. See section 12. Environmental precautions: Do not allow material to enter drains or water courses. Section7. Handling and storage Handling:This product should be handled only by, or under the close supervision of, those properly qualified in the handling and use of potentially hazardous chemicals, who should take into account the fire, health and chemical hazard data given on this sheet. Storage:Store in closed vessels, refrigerated. Section8. Exposure Controls / Personal protection Engineering Controls: Use only in a chemical fume hood. Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles. General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse. Section9. Physical and chemical properties Appearance:Not specified Boiling point:No data Melting point:No data Flash point:No data Density:No data Molecular formula:C7H5BrF2 Molecular weight:207.0 Section10. Stability and reactivity Conditions to avoid: Heat, flames and sparks. Materials to avoid: Oxidizing agents. Possible hazardous combustion products: Carbon monoxide, hydrogen fluoride, hydrogen bromide. Section11. Toxicological information No data. Section12. Ecological information No data. Section13. Disposal consideration Arrange disposal as special waste, by licensed disposal company, in consultation with local waste disposal authority, in accordance with national and regional regulations. Section14. Transportation information Non-harzardous for air and ground transportation. Section15. Regulatory information No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302, or have known CAS numbers that exceed the threshold reporting levels established by SARA Title III, Section 313. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 风险声明 (欧洲): 36/37/38
• 安全声明 (欧洲): 26-37-60
• 危险品运输编码: 1993
• 包装等级: Ⅲ
• 海关编码: 2903999090

合成路线

1122-91-4 ~83% 51776-71-7

文献：Pfizer Inc. Patent: US2012/214791 A1, 2012 ; Location in patent: Page/Page column 27 ; US 20120214791 A1

109050-30-8 ~82% 51776-71-7

文献：Mizuta, Satoshi; Stenhagen, Ida S.R.; O'Duill, Miriam; Wolstenhulme, Jamie; Kirjavainen, Anna K.; Forsback, Sarita J.; Tredwell, Matthew; Sandford, Graham; Moore, Peter R.; Huiban, Mickael; Luthra, Sajinder K.; Passchier, Jan; Solin, Olof; Gouverneur, Veronique Organic Letters, 2013 , vol. 15, # 11 p. 2648 - 2651

913574-93-3 ~% 51776-71-7

文献：Fujikawa, Kenichi; Fujioka, Yasutaka; Kobayashi, Akira; Amii, Hideki Organic Letters, 2011 , vol. 13, # 20 p. 5560 - 5563

589-87-7 1438388-96-5 ~52% 51776-71-7

文献：Prakash, G. K. Surya; Ganesh, Somesh K.; Jones, John-Paul; Kulkarni, Aditya; Masood, Kamil; Swabeck, Joseph K.; Olah, George A. Angewandte Chemie - International Edition, 2012 , vol. 51, # 48 p. 12090 - 12094 Angew. Chem., 2012 , vol. 124, # 48 p. 12256 - 12260,5

589-87-7 ~% 51776-71-7

文献：Fujikawa, Kenichi; Fujioka, Yasutaka; Kobayashi, Akira; Amii, Hideki Organic Letters, 2011 , vol. 13, # 20 p. 5560 - 5563

1878-68-8 ~% 51776-71-7

文献：Mizuta, Satoshi; Stenhagen, Ida S.R.; O'Duill, Miriam; Wolstenhulme, Jamie; Kirjavainen, Anna K.; Forsback, Sarita J.; Tredwell, Matthew; Sandford, Graham; Moore, Peter R.; Huiban, Mickael; Luthra, Sajinder K.; Passchier, Jan; Solin, Olof; Gouverneur, Veronique Organic Letters, 2013 , vol. 15, # 11 p. 2648 - 2651

海关

海关编码	2903999090
中文概述	2903999090 其他芳烃卤化衍生物. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:5.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%