61-00-7

• 常用中文名：乙酰丙嗪
• 常用英文名：acepromazine
• CAS号：61-00-7
• 分子式：C₁₉H₂₂N₂OS
• 分子量：326.45600
• 相关类别： 原料药 神经系统用药 抗精神病药
• 发布时间：2018-05-21 08:00:00
• 更新时间：2026-07-12 12:18:55

名称

• 中文名: 乙酰丙嗪
• 英文名: acepromazine
• 英文别名: acromazine //BP; 1-[10-(3-dimethylamino-propyl)-phenothiazin-2-yl]-ethanone; 1-[10-(3-dimethylaminopropyl)phenothiazin-2-yl]ethanone; Vetranquil; 1-[10-(3-Dimethylamino-propyl)-phenothiazin-2-yl]-aethanon; KETONE,10-(3-(DIMETHYLAMINO)PROPYL)PHENOTHIAZIN-2-YLMETHYL; Aids-013600; 10-(3-DIMETHYLAMINOPROPYL)PHENOTHIAZINE-3-ETHYLONE; Acetopromazine; acromazine; 10-[3-[Dimethylamino] propyl] phenothiazin-2-yl methyl ketone; Ethanone, -3-(dimethylamino)propyl-10H-phenothiazin-2-yl; Acetylperazine; Aids013600; Acromazine DISCONTINUED, offer A130900; Acetopromazine maleate salt; Acromazine (base and/or unspecified salts); Acetylpromazine; 3-6 (Maleate); 1522CB; Notensil

物化性质

• 密度: 1.1075 (rough estimate)
• 沸点: bp0.5 220-240°
• 分子式: C₁₉H₂₂N₂OS
• 分子量: 326.45600
• 精确质量: 326.14500
• PSA: 48.85000
• LogP: 4.50860
• 折射率: 1.5950 (estimate)
• 储存条件: 库房通风低温干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : OB2275000 CHEMICAL NAME : Ketone, 10-(3-(dimethylamino)propyl)phenothiazin-2-yl methyl CAS REGISTRY NUMBER : 61-00-7 LAST UPDATED : 199707 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C19-H22-N2-O-S MOLECULAR WEIGHT : 326.49 WISWESSER LINE NOTATION : T C666 BN ISJ B3N1&1 EV1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 140 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 24,136,1961 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 113,53,1957 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 350 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : RMNIBN Revista Medico-Chirurgicala. Medical-Surgical Journal. (Societatea de Medici si Naturalisti, 16 Bulevardul Independentei, Iasi, Romania) V.35- 1924- Volume(issue)/page/year: 81,105,1977 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 130 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 113,53,1957 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 59 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 115,1,1958 *** REVIEWS *** TOXICOLOGY REVIEW JMSCA9 Journal of Mental Science. (London, UK) V.4-108, 1857-1962. For publisher information, see BJPYAJ. Volume(issue)/page/year: 106,755,1960 TOXICOLOGY REVIEW IDPYAK Industrial Pharmacology. (Mount Kisco, NY) V.1-3, 1974-79. Discontinued. Volume(issue)/page/year: 1,203,1974

安全

• 海关编码: 2934300000

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海关

海关编码	2934300000
中文概述	2934300000. 含一个吩噻嗪环系的化合物(吩噻嗪环系不论是否氢化,化合物未经进一步稠合的 ). 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%