70891-37-1

• 常用中文名：Nafimidone
• 常用英文名：Nafimidone
• CAS号：70891-37-1
• 分子式：C₁₅H₁₃ClN₂O
• 分子量：272.73000
• 发布时间：2016-04-05 10:09:50
• 更新时间：2024-01-11 18:04:36

名称

• 英文名: 2-imidazol-1-yl-1-naphthalen-2-ylethanone,hydrochloride
• 英文别名: 2-imidazol-1-yl-1-naphthalen-2-yl-ethanone hydrochloride; 2-(1H-Imidazol-1-yl)-1-(2-naphthalenyl)ethanone monohydrochloride; Nafimidone hydrochloride (USAN); Ethanone,2-(1H-imidazol-1-yl)-1-(2-naphthalenyl)-,monohydrochloride; 2-(1-Imidazolylacetyl)naphthalene hydrochloride; 2'-ACETONAPHTHONE,2-(1-IMIDAZOLYL)-,HYDROCHLORIDE; Nafimidone HCl; 1-(2-Naphthoylmethyl)imidazole hydrochloride; 2-(1H-imidazol-1-yl)-1-(naphthalen-2-yl)ethanone hydrochloride; Nafimidone hydrochloride

物化性质

• 分子式: C₁₅H₁₃ClN₂O
• 分子量: 272.73000
• 精确质量: 272.07200
• PSA: 34.89000
• LogP: 3.72120

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : KM5780880 CHEMICAL NAME : Ethanone, 2-(1H-imidazol-1-yl)-1-(2-naphthalenyl)-, monohydrochloride CAS REGISTRY NUMBER : 70891-37-1 LAST UPDATED : 199203 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C15-H12-N2-O.Cl-H MOLECULAR WEIGHT : 272.75 WISWESSER LINE NOTATION : L66J BV1- AT5N CNJ &GH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 504 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 29,1577,1986 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 420 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 120,185,1981 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 210 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold REFERENCE : BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 120,185,1981

安全

• 海关编码: 2934999090

合成路线

288-32-4 613-54-7 ~38% 70891-37-1

文献：Roman, Gheorghe; Vlahakis, Jason Z.; Vukomanovic, Dragic; Nakatsu, Kanji; Szarek, Walter A. ChemMedChem, 2010 , vol. 5, # 9 p. 1541 - 1555

上下游产品

上游产品  2
288-32-4 613-54-7
下游产品  3
70891-42-8 70891-65-5 71009-17-1

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%