100492-04-4

• 常用中文名：7-氯-1-(2,4-二氟苯)-6-氟-4-酮-1,4-二氢-1,8-萘啶-3-羧酸
• 常用英文名：Tosufloxacin pharmaceutical intermediate
• CAS号：100492-04-4
• 分子式：C₁₅H₆ClF₃N₂O₃
• 分子量：354.668
• 发布时间：2019-01-13 11:55:29
• 更新时间：2024-01-19 16:23:26

名称

• 中文名: 7-氯-1-(2,4-二氟苯)-6-氟-4-酮-1,4-二氢-1,8-萘啶-3-羧酸
• 英文名: 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid
• 中文别名: 7-氯-1-(2,4-二氟苯基)-6-氟-4-氧代-1,4-二氢-1,8-萘啶-3-羧酸
• 英文别名: 7-Chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid; 7-chloro-1-(o,p-difluorophenyl)1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid; 7-Chloro-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid; Tosufloxacin pharmaceutical intermediate; 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro 4-oxo-1,8-naphthyridine-3-carboxylic acid; 1,8-Naphthyridine-3-carboxylicacid,7-chloro-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo; 1,8-Naphthyridine-3-carboxylic acid, 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-; 1-(2,4-difluoroanlino)-6-fluoro-7-chloro-1,4-dihydro-4-oxo-18-naphthylidine-3-carboxylic acid; 7-chloro-1-(2,4-difluoro-phenyl)-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid; T66 BV EN GNJ CVQ ER BF DF& HG IF; 1-(2,4-difluorophenyl)-6-fluoro-7-chloro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid

物化性质

• 密度: 1.7±0.1 g/cm3
• 沸点: 518.2±50.0 °C at 760 mmHg
• 分子式: C₁₅H₆ClF₃N₂O₃
• 分子量: 354.668
• 闪点: 267.2±30.1 °C
• 精确质量: 354.001892
• PSA: 72.19000
• LogP: 2.41
• 蒸汽压: 0.0±1.4 mmHg at 25°C
• 折射率: 1.638

合成路线

100491-29-0 ~96% 100492-04-4

文献：US4704459 A1, ;

96568-04-6 ~% 100492-04-4

文献：US2014/73631 A1, ;

100490-99-1 ~% 100492-04-4

文献：US2014/73631 A1, ;

82671-03-2 ~% 100492-04-4

文献：US2014/73631 A1, ;

82671-06-5 ~% 100492-04-4

文献：US2014/73631 A1, ;

96568-02-4 ~% 100492-04-4

文献：US2014/73631 A1, ;

上下游产品

上游产品  6
100491-29-0 96568-04-6 100490-99-1 82671-03-2
82671-06-5 96568-02-4
下游产品  0