112849-17-9

• 常用中文名：钙泊三醇中间体-9
• 常用英文名：(R,E)-4-((1R,3As,7Ar,E)-4-((E)-2-((3S,5R)-3,5-Bis(Tert-Butyldimethylsilyloxy)-2-Methylenecyclohexylidene)Ethylidene)-7A-Methyloctahydro-1H-Inden-1-Yl)-1-Cyclopropylpent-2-En-1-One
• CAS号：112849-17-9
• 分子式：C₃₉H₆₆O₃Si₂
• 分子量：639.110
• 发布时间：2018-08-29 12:48:23
• 更新时间：2026-06-30 10:02:25

名称

• 中文名: (2E,4R)-4-[(1R,3AS,4E,7AR)-4-[(2E)-2-[(3S,5R)-3,5-双[[(叔丁基)二甲基硅]氧基]-2-亚甲基环己亚基]乙烯基]八氢-7A-甲基-1H-茚-1-基]-1-环丙基-2-戊烯-1-酮
• 英文名: (2E,4R)-4-[(1R,3aS,4E,7aR)-4-[(2E)-2-[(3S,5R)-3,5-Bis[[(tert-butyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene]ethylidene]octahydro-7a-methyl-1H-inden-1-yl]-1-cyclopropyl-2-penten-1-one
• 中文别名: (2E,4R)-4-[(1R,3AS,4E,7-4-[(2E)-2-[(3S,5R)-3,5-双[[(1,1-二甲基乙基)二甲基硅酯]氧基]-2-亚甲基环亚己基]亚乙基]八氢-7A-甲基-1H-茚-1-基]-1-环丙基-2-戊烯-1-酮; (2E,4R)-4-[(1R,3AS,4E,7AR)-4-[(2E)-2-[(3S,5R)-3,5-双[[(1,1-二甲基乙基)二甲基硅酯]氧基]-2-亚甲基环亚己基]亚乙基]八氢-7A-甲基-1H-茚-1-基]-1-环丙基-2-戊烯-1-酮; 卡泊三醇中间体-9; (2E,4R)-4-[(1R,3AS,4E,7-4-[(2E)-2-[(3S,5R)-3,5-双[[(叔丁基)二甲基硅]氧基]-2-亚甲基环己亚基]乙烯基]八氢-7A-甲基-1H-茚-1-基]-1-环丙基-2-戊烯-1-酮; 卡泊三醇中间体/112-9; 卡泊三醇杂质11; 24-羰基-1,3-双TBS-反式-钙泊三醇; 24-羰基-1,3-双TBS-反式-钙泊三醇/(R,E)-4-((1R,3aS,7,E)-4-((E)-2-((3S,5R)-3,5-bis((tert-butyldimethyl-silyl)oxy)-2-methylenecyclohexyl-idene) ethylidene)-7a-methyl octahydro-1H-inden-1-yl)-1-cyclopropylpent-2-en-1-one
• 英文别名: 2-Penten-1-one, 4-[(1R,3aS,4E,7-4-[(2E)-2-[(3S,5R)-3,5-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene]ethylidene]octahydro-7a-methyl-1H-inden-1-yl]-1-cyclopropyl-, (2E,4R); (1a,3b,5E,7E,22E)-24-Cyclopropyl-1,3-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-9,10-secochola-5,7,10,22-tetraen-24-one; (1S,3R,5E,7E,22E)-1,3-Bis{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-26,27-cyclo-9,10-secocholesta-5,7,10,22-tetraen-24-one; 20(R),1(S),3(R)-bis(tert-butyldimethylsilyloxy)-20-(3'-cyclopropyl-3'-oxoprop-1'(E)-enyl)-9,10-secopregna-5(E),7(E),10(19)-triene; 24-carbonyl-1,3-bi-TBS-trans-Calcipotriol; (1S,3R,5E,7E,22E)-1,3-Bis{[tert-butyl(dimethyl)silyl]oxy}-26,27-cyclo-9,10-secocholesta-5,7,10,22-tetraen-24-one; 1(S),3(R).20(R)-BIS(TERT-BUTYLDIMETHYLSILYLOXY)-20-(3'-CYCLOPROPYL-3'-OXYPROP-1'(E)-ENYL)-9,10-SECOPREGNA-5(E),10(19)TRIENE; Calcipotriol Intermediate 9; Calcipotriol (Calcipotriene) intermediate; (R,E)-4-((1R,3aS,7aR,E)-4-((E)-2-((3S,5R)-3,5-bis(tert-butyldiMethylsilyloxy)-2-Methylenecyclohexylidene)ethylidene)-7a-Methyloctahydro-1H-inden-1-yl)-1-cyclopropylpent-2-en-1-one; 2-Penten-1-one,4-[(1R,3aS,4E,7aR)-4-[(2E)-2-[(3S,5R)-3,5-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene]ethylidene]octahydro-7a-methyl-1H-inden-1-yl]-1-cyclopropyl-,(2E,4R); (1S,3R,20R)-bis(tert-butyldimethylsilyloxy)-20-(3'-cyclopropyl-3'-oxyprop-1'(E)-enyl)-9,10-secopregna-5(E),7(E),10(19)-triene; 1(S),3(R).20(R)-BIS(TERT-BUTYLDIMETHYLSILYLOXY)-20-(3'-CYCLOPROPYL-3'-OXYPROP-1'(E)-ENYL)-9,10-SECOPREGNA-5(E),10TRIENE; (1a,3b,5E,7E,22E)-24-Cyclopropyl-1,3-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-9,10-secochola-5,7,10(19),22-tetraen-24-one; InterMediate G6/(2E,4R)-4-[(1R,3aS,4E,7-4-[(2E)-2-[(3S,5R)-3,5-Bis[[(tert-butyl)diMethylsilyl]oxy]-2-Methylenecyclohexylidene]ethylidene]octahydro-7a-Methyl-1H-inden-1-yl]-1-cyclopropyl-2-penten-1-one; (R,E)-4-((1R,3aS,7,E)-4-((E)-2-((3S,5R)-3,5-bis(tert-butyldiMethylsilyloxy)-2-Methylenecyclohexylidene)ethylidene)-7a-Methyloctahydro-1H-inden-1-yl)-1-cyclopropylpent-2-en-1-one; Calcipotriol Impurity 11; (2E,4R)-4-[(1R,3aS,4E,7-4-[(2E)-2-[(3S,5R)-3,5-Bis[[(tert-butyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene]ethylidene]octahydro-7a-methyl-1H-inden-1-yl]-1-cyclopropyl-2-penten-1-one; (5E)-1,3-Bis-O-(tert-Butyldimethylsilyl)-24-oxo-calcipotriene; (2E,4R)-4-[(1R,3aS,4E,7-4-[(2E)-2-[(3S,5R)-3,5-Bis[[(tert

物化性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 628.2±55.0 °C at 760 mmHg
• 分子式: C₃₉H₆₆O₃Si₂
• 分子量: 639.110
• 闪点: 277.1±27.0 °C
• 精确质量: 638.455078
• PSA: 35.53000
• LogP: 12.08
• 外观性状: 白色晶体
• 蒸汽压: 0.0±1.8 mmHg at 25°C
• 折射率: 1.512
• 储存条件: 室温

合成路线

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