79902-31-1

• 常用中文名：4-(叔丁基二甲基甲硅烷氧基)-6-[2-(8-羟基-2,6-二甲基-1,2,6,7,8,8a-六氢萘)-乙基]-四氢吡喃-2-酮
• 常用英文名：4-(TERT-BUTYLDIMETHYLSILANYLOXY)-6-[2-(8-HYDROXY-2,6-DIMETHYL-1,2,6,7,8,8A-HEXAHYDRONAPHTHALEN-1-YL)ETHYL]TETRAHYDROPYRAN-2-ONE
• CAS号：79902-31-1
• 分子式：C₂₅H₄₂O₄Si
• 分子量：434.68400
• 发布时间：2018-11-28 08:26:07
• 更新时间：2024-04-03 12:39:03

名称

• 中文名: 4-(叔丁基二甲基甲硅烷氧基)-6-[2-(8-羟基-2,6-二甲基-1,2,6,7,8,8a-六氢萘)-乙基]-四氢吡喃-2-酮
• 英文名: (4R,6R)-6-[2-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl]-4-[tert-butyl(dimethyl)silyl]oxyoxan-2-one
• 英文别名: 1,7-Dioxaspiro[4.4]nonane-2,6-dione,8-(1,2-dihydroxyethyl)-9-hydroxy-4-(p-hydroxyphenyl); 6(R)-[2-[8(S)-hydroxy-2(S); Leucodrin; (4R,6R)-6-[2-((1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthyl)ethyl]-4-[(tert-butyldimethylsilyl)oxy]-3,4,5,6-tetrahydro-2H-pyran-2-one; (4R,6R)-4-(tert-butyldimethylsilyloxy)-6-(2-((1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)ethyl)tetrahydro-2H-pyran-2-one; 6(R)-[2-[8(S)-Hydroxy-2(S),6(R)-dimethyl-1,2,6,7,8,8a-(R)-hexahydronaphthyl-1(S)]ethyl]-4(R)-(tert-butyldimethylsilyloxy)-3,4,5,6-tetrahydro-2H-pyran-2-one; 6(R)-[2-(8(S)-hydroxy-2(S),6(R)-dimethyl-1,2,6,7,8,8a(R)-hexahydronaphth-1(S)-yl)-ethyl]-4(R)-(dimethyl-tert-butylsilyl-oxy)-3,4,5,6-tetrahydro-2H-pyran-2-one; 6(R)-[2-[8'(S)-hydroxy-2'(S),6'(R)-dimethyl-1',2',6',7',8',8a'(R)-hexahydronaphthalene-1'(S)-yl]-ethyl]-4(R)-(dimethyl-tert-butylsilyloxy)-3,4,5,6-tetrahydro-2H-pyran-2-one; 6(R)-dimethyl-1,2,6,7,8,8a(R)-hexahydronaphthyl-1(S)]ethyl]-4(R)-(tert-butyldimethylsilyloxy)-3,4,5,6-tetrahydro-2H-pyran-2-one; (4R,5S,8R)-8r-((S)-1,2-dihydroxy-ethyl)-9t-hydroxy-4-(4-hydroxy-phenyl)-1,7-dioxa-spiro[4.4]nonane-2,6-dione; tert-butyldimethylsiloxymonacolin J; (4R,5S,8R)-8r-((S)-1,2-Dihydroxy-aethyl)-9t-hydroxy-4-(4-hydroxy-phenyl)-1,7-dioxa-spiro[4.4]nonan-2,6-dion

物化性质

• 密度: 1.047g/cm3
• 沸点: 540.396ºC at 760 mmHg
• 分子式: C₂₅H₄₂O₄Si
• 分子量: 434.68400
• 闪点: 280.622ºC
• 精确质量: 434.28500
• PSA: 55.76000
• LogP: 5.62800
• 折射率: 1.514

合成路线

151006-15-4 18162-48-6 ~99% 79902-31-1

文献：CJ CORP. Patent: WO2004/96789 A1, 2004 ; Location in patent: Page 10-11; 8 ;

75-07-0 143746-93-4 ~0% 79902-31-1 136432-18-3 详细

文献：Hartman; Halczenko; Duggan; Imagire; Smith; Pitzenberger; Fitzpatrick; Alberts; Bostedor; Chao; Germershausen; Gilfillan; Hunt Journal of Medicinal Chemistry, 1992 , vol. 35, # 21 p. 3813 - 3821

75330-75-5 ~% 79902-31-1

文献：Organic and Biomolecular Chemistry, , vol. 1, # 1 p. 50 - 59

132748-10-8 ~% 79902-31-1

文献：Organic and Biomolecular Chemistry, , vol. 1, # 1 p. 50 - 59

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