中文名 | 3-(4’-哌啶基)-1H-吲哚 |
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英文名 | 3-(Piperidin-4-yl)-1H-indole |
中文别名 | 3-哌嗪-4-基-1H-吲哚 |
英文别名 |
3-piperidin-4-yl-1H-indole
3-(4-Piperidinyl)-1H-indole MFCD01764670 1H-Indole, 3-(4-piperidinyl)- EINECS 241-425-3 3-(Piperidin-4-yl)-1H-indole |
密度 | 1.1±0.1 g/cm3 |
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沸点 | 388.6±35.0 °C at 760 mmHg |
熔点 | 222-223ºC |
分子式 | C13H16N2 |
分子量 | 200.279 |
闪点 | 188.8±25.9 °C |
精确质量 | 200.131348 |
PSA | 27.82000 |
LogP | 2.31 |
外观性状 | 固体;White to Light yellow powder to crystal |
蒸汽压 | 0.0±0.9 mmHg at 25°C |
折射率 | 1.623 |
储存条件 | 室温 |
Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 34 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Causes burns. Potential Health Effects Eye: Causes eye burns. Skin: Causes skin burns. Ingestion: Causes gastrointestinal tract burns. Inhalation: Causes chemical burns to the respiratory tract. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Do not induce vomiting. Get medical aid immediately. Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use foam, dry chemical, or carbon dioxide. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood. Storage: Store in a cool, dry place. Store in a tightly closed container. Corrosives area. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 17403-09-7: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: Not available. Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 222 - 224 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C13H16N2 Molecular Weight: 200.28 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 17403-09-7 unlisted. LD50/LC50: Not available. Carcinogenicity: 3-Piperidin-4-yl-1H-indole - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: AMINES, SOLID, CORROSIVE, N.O.S.* Hazard Class: 8 UN Number: 3259 Packing Group: III IMO Shipping Name: AMINES, SOLID, CORROSIVE, N.O.S. Hazard Class: 8 UN Number: 3259 Packing Group: III RID/ADR Shipping Name: AMINES, SOLID, CORROSIVE, N.O.S. Hazard Class: 8 UN Number: 3259 Packing group: III Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: C Risk Phrases: R 34 Causes burns. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 17403-09-7: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 17403-09-7 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 17403-09-7 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
危害码 (欧洲) | C: Corrosive; |
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风险声明 (欧洲) | R34 |
安全声明 (欧洲) | S26-S36/37/39-S45 |
危险品运输编码 | UN 3259 |
海关编码 | 2933990090 |
~99% 17403-09-7 |
文献:GRUeNENTHAL GMBH Patent: WO2004/43949 A1, 2004 ; Location in patent: Page/Page column 30 ; |
~75% 17403-09-7 |
文献:Burm, Brigitte E.A; Gremmen, Christiaan; Wanner, Martin J; Koomen, Gerrit-Jan Tetrahedron, 2001 , vol. 57, # 10 p. 2039 - 2049 |
~% 17403-09-7 |
文献:Journal of Medicinal Chemistry, , vol. 47, # 25 p. 6326 - 6337 |
~% 17403-09-7 |
文献:Journal of Medicinal Chemistry, , vol. 47, # 25 p. 6326 - 6337 |
~% 17403-09-7 |
文献:European Journal of Medicinal Chemistry, , vol. 44, # 4 p. 1710 - 1717 |
~% 17403-09-7 |
文献:WO2011/143444 A2, ; |
~% 17403-09-7 |
文献:European Journal of Medicinal Chemistry, , vol. 63, p. 484 - 500 |
~% 17403-09-7 |
文献:European Journal of Medicinal Chemistry, , vol. 63, p. 484 - 500 |
上游产品 7 | |
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下游产品 6 | |
海关编码 | 2933990090 |
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中文概述 | 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0% |
申报要素 | 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期 |
Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |