376584-30-4

• 常用中文名：(3,4-二氢-6-(4,4,5,5-四甲基-1,3,2-二氧杂环戊硼烷-2-基)异喹啉-1(2H)-酮
• 常用英文名：3,4-DIHYDRO-6-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ISOQUINOLIN-1(2H)-ONE
• CAS号：376584-30-4
• 分子式：C₁₅H₂₀BNO₃
• 分子量：273.135
• 发布时间：2018-12-25 12:19:34
• 更新时间：2026-08-14 07:49:53

名称

• 中文名: 3,4-二氢-6-(4,4,5,5-四甲基-1,3,2-二噁硼烷)-1(2h)-异喹啉酮
• 英文名: 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-isoquinolin-1-one
• 中文别名: 3,4-二氢异喹啉-1(2H)-酮-6-硼酸频哪醇酯; 3,4二氢异喹啉-1-酮-6-硼酸酯; 3,4-二氢-6-(4,4,5,5-四甲基-1,3,2-二氧杂硼烷-2-基)-1(2h)-异喹啉酮; 3,4-二氢-6-(4,4,5,5-四甲基-1,3,2-二噁硼烷)-1(2H)-异喹啉酮; 1-氧代-1,2,3,4-四氢异喹啉-6-硼酸频哪醇酯; 6-(4,4,5,5-四甲基-1,3,2-二氧硼杂环己烷-2-基)-3,4-二氢异喹啉-1(2H)-酮; 6-(4,4,5,5-四甲基-1,3,2-二氧杂环戊硼烷-2-基)-3,4-二氢异喹啉-1(2H)-酮; 6-(4,4,5,5-四甲基-1,3,2-二氧硼杂环戊烷-2-基)-3,4-二氢异喹啉-1(2H)-酮; 3,4-二氢-1(2H)-异喹啉酮-6-硼酸频哪醇酯
• 英文别名: 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinolin-1(2H)-one; 3,4-DIHYDRO-6-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1(2H)-ISOQUINOLINONE; 6-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,4-dihydro-2H-isoquinolin-1-one; 1-Oxo-1,2,3,4-tetrahydroisoquinoline-6-boronic acid, pinacol ester; 3,4-dihydro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinolin-1(2H)-one; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-1(2H)-isoquinolinone; 3,4-Dihydro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinolin-1(2H)-one, 1-Oxo-1,2,3,4-tetrahydro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinoline; 3,4-Dihydro-1(2H)-isoquinolinone-6-boronic acid pinacol ester; y8916; 1(2H)-Isoquinolinone, 3,4-dihydro-6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 494.6±45.0 °C at 760 mmHg
• 分子式: C₁₅H₂₀BNO₃
• 分子量: 273.135
• 闪点: 252.9±28.7 °C
• 精确质量: 273.153625
• PSA: 47.56000
• LogP: 1.60050
• 蒸汽压: 0.0±1.3 mmHg at 25°C
• 折射率: 1.540
• 储存条件: 2-8°C

安全

• 危害码 (欧洲): Xi
• 海关编码: 2934999090

合成路线

147497-32-3 73183-34-3 ~26% 376584-30-4

文献：Spicer, Julie A.; Lena, Gersande; Lyons, Dani M.; Huttunen, Kristiina M.; Miller, Christian K.; O'Connor, Patrick D.; Bull, Matthew; Helsby, Nuala; Jamieson, Stephen M. F.; Denny, William A.; Ciccone, Annette; Browne, Kylie A.; Lopez, Jamie A.; Rudd-Schmidt, Jesse; Voskoboinik, Ilia; Trapani, Joseph A. Journal of Medicinal Chemistry, 2013 , vol. 56, # 23 p. 9542 - 9555

147497-32-3 ~94% 376584-30-4

文献：Incyte Corporation; Zhuo, Jincong; Xu, Meizhong; Qian, Ding-Quan Patent: US2014/171405 A1, 2014 ; Location in patent: Page/Page column ;

1279816-33-9 ~% 376584-30-4

文献：Spicer, Julie A.; Lena, Gersande; Lyons, Dani M.; Huttunen, Kristiina M.; Miller, Christian K.; O'Connor, Patrick D.; Bull, Matthew; Helsby, Nuala; Jamieson, Stephen M. F.; Denny, William A.; Ciccone, Annette; Browne, Kylie A.; Lopez, Jamie A.; Rudd-Schmidt, Jesse; Voskoboinik, Ilia; Trapani, Joseph A. Journal of Medicinal Chemistry, 2013 , vol. 56, # 23 p. 9542 - 9555

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海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%