105394-83-0

• 常用中文名：脱羧环丙沙星
• 常用英文名：Decarboxy Ciprofloxacin
• CAS号：105394-83-0
• 分子式：C₁₆H₁₈FN₃O
• 分子量：287.33200
• 发布时间：2019-01-15 00:54:59
• 更新时间：2026-08-02 12:38:12

名称

• 中文名: 环丙沙星杂质E
• 英文名: 1-cyclopropyl-6-fluoro-7-piperazin-1-ylquinolin-4-one
• 中文别名: 1-环丙基-6-氟-7-(1-哌嗪基)-4(1H)-喹啉酮; 去羧基环丙沙星; 环丙沙星杂质Ⅴ(环丙沙星杂质 E) 1-环丙基-6-氟-7-(哌嗪1-基)喹啉-4-(1H)酮; 1-环丙基-6-氟-7-(哌嗪-1-基)喹啉-4(1H)-酮; 盐酸环丙沙星杂质Ⅴ杂质E1-环丙基-6-氟-7-(哌嗪1-基)喹啉-4-(1H)酮; 环丙沙星杂质Ⅴ（环丙沙星杂质 E） 1-环丙基-6-氟-7-(哌嗪1-基)喹啉-4-(1H)酮; 盐酸环丙沙星杂质E 标准品; 环丙沙星杂质E(盐酸盐); 盐酸环丙沙星杂质E; 环丙沙星杂质5(环丙沙星杂质E)
• 英文别名: 1-Cyclopropyl-6-fluoro-7-(piperazin; Decboxy Ciprofloxacin; Ciprofloxacin IMpurity E //BP; 1-Cyclopropyl-6-fluoro-7-(piperazin-1-yl)quinolin-4(1H)-one (Decboxylated Compound); Ciprofloxacin Impurity E(HCl); 7-(piperazin-1-yl)-1-cyclopropyl-6-fluoroquinolin-4-one; Ciprofloxacin Hydrochloride Impurity E; Ciprofloxacin Impurity EQ: What is Ciprofloxacin Impurity E Q: What is the CAS Number of Ciprofloxacin Impurity E Q: What is the storage condition of Ciprofloxacin Impurity E Q: What e the applications of Ciprofloxacin Impurity E; 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oyo-7(1-piperazinyl)-quinoline; 1-Cyclopropyl-6-fluoro-7-(piperazin-1-yl)quinolin-4(1H)-one; Ciprofloxacin ImpuritⅤ:(Ciprofloxacin Impurity E)1-Cyclopropyl-6-fluoro-7-(piperazin-1-yl)quinolin-4(1H)-one; Ciprofloxacin IMpurity E; Ciprofloxacin Impurity E HClQ: What is Ciprofloxacin Impurity E HCl Q: What is the CAS Number of Ciprofloxacin Impurity E HCl Q: What is the storage condition of Ciprofloxacin Impurity E HCl; Ciprofloxacin Impurity-E (Decboxy Ciprofloxacin); Ciprofloxacin impurity 4/Ciprofloxacin Impurity E/ Decboxy Ciprofloxacin/1-cyclopropyl-6-fluoro-7-(piperazin-1-yl)quinolin-4(1H)-one; 4(1H)-Quinolinone, 1-cyclopropyl-6-fluoro-7-(1-piperazinyl); Fluoroquinolonic acid E; 1-cyclopropyl-6-fluoro-7-(1-piperazinyl)-4(1H)-quinolinone; 1-Cyclopropyl-6-fluoro-7-(1-piperazinyl)-4(1H)-quinolinone; Ciprofloxacin Impurity E/Decboxy Ciprofloxacin; Ciprofloxacin Hydrochloride Impurity Ⅴ:Ciprofloxacin Impurity E; SQ-4002; Ciprofloxacin Impurity 5(Ciprofloxacin Impurity E)

物化性质

• 密度: 1.327g/cm3
• 沸点: 496.641ºC at 760 mmHg
• 分子式: C₁₆H₁₈FN₃O
• 分子量: 287.33200
• 闪点: 254.159ºC
• 精确质量: 287.14300
• PSA: 37.27000
• LogP: 2.27890
• 蒸汽压: 0mmHg at 25°C
• 折射率: 1.631
• 储存条件: 2-8°C， 充氩

安全

• 海关编码: 2933990090

合成路线

93107-08-5 ~30% 105394-83-0

文献：Marks, Kevin R.; Malik, Muhammad; Mustaev, Arkady; Hiasa, Hiroshi; Drlica, Karl; Kerns, Robert J. Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 15 p. 4585 - 4588

85721-33-1 ~93% 105394-83-0

文献：Dar Al Dawa Development, and Investment Co. Patent: EP1245566 A1, 2002 ; Location in patent: Page 2-3 ;

1337918-18-9 ~% 105394-83-0

文献：Nguyen, Son T.; Ding, Xiaoyuan; Butler, Michelle M.; Tashjian, Tommy F.; Peet, Norton P.; Bowlin, Terry L. Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 19 p. 5961 - 5963

85721-33-1 ~% 105394-83-0 93107-11-0

文献：Helvetica Chimica Acta, , vol. 84, # 9 p. 2508 - 2519

上下游产品

上游产品  3
93107-08-5 85721-33-1 1337918-18-9
下游产品  0

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%