11032-41-0

• 常用中文名：甲磺酸二氢麦角胺
• 常用英文名：dihydroergotamine mesylate
• CAS号：11032-41-0
• 分子式：C₃₄H₄₁N₅O₈S
• 分子量：679.783
• 相关类别： 原料药 循环系统用药 周围血管扩张药
• 发布时间：2018-03-11 08:00:00
• 更新时间：2024-01-06 10:18:29

名称

• 中文名: 甲磺酸二氢麦角胺
• 英文名: dihydroergotamine mesylate
• 英文别名: ergotaman, 9,10-dihydro-12'-hydroxy-2'-methyl-3',6',18-trioxo-5'-(phenylmethyl)-, (5α,5'α,8α)-, methanesulfonate (1:1) (salt); Ergotaman, 9,10-dihydro-12'-hydroxy-2'-methyl-3',6',18-trioxo-5'-(phenylmethyl)-, (5'α)-, methanesulfonate (1:1) (salt); (5α,5'α,8α)-5'-Benzyl-12'-hydroxy-2'-methyl-3',6',18-trioxo-9,10-dihydroergotaman methanesulfonate (1:1); (5'α)-5'-Benzyl-12'-hydroxy-2'-methyl-3',6',18-trioxo-9,10-dihydroergotaman methanesulfonate (1:1)

物化性质

• 分子式: C₃₄H₄₁N₅O₈S
• 分子量: 679.783
• 精确质量: 679.267578
• PSA: 180.96000
• LogP: 2.87050
• 外观性状: powder | white
• 水溶解性: methanol: 21 mg/mL

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : KE8775000 CHEMICAL NAME : Ergotoxine, dihydro- CAS REGISTRY NUMBER : 11032-41-0 LAST UPDATED : 199509 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 71 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 31,53,1968

安全

• 危害码 (欧洲): Xn: Harmful;
• 风险声明 (欧洲): 20/21/22
• 安全声明 (欧洲): 36
• WGK德国: 3
• RTECS号: KE7920000