71083-59-5

• 常用中文名：4-氧代-1,4-二氢喹啉-3-甲腈
• 常用英文名：4-Hydroxychinolin-3-carbonitril
• CAS号：71083-59-5
• 分子式：C₁₀H₆N₂O
• 分子量：170.167
• 发布时间：2018-12-25 23:42:22
• 更新时间：2024-01-12 13:27:42

名称

• 中文名: 4-氧代-1,4-二氢喹啉-3-甲腈
• 英文名: 4-Hydroxy-3-quinolinecarbonitrile
• 英文别名: 4-quinolone-3-carbonitrile; 4-Oxo-1,4-dihydrochinolin-3-carbonitril; 4-Hydroxychinolin-3-carbonitril; 4-oxo-1,4-dihydro-2,6-pyridinedicarboxylic acid; 1,4-dihydro-4-oxoquinoline-3-carbonitrile; 4-oxo-1,4-dihydropyridine-2,6-dicarboxylic acid; 4-PYRIDONE-2,6-DICARBOXYLIC ACID; 1,4-dihydro-4-oxo-2,6-pyridinedicarboxylic acid; 4-oxo-1,4-dihydro-quinoline-3-carbonitrile; .HELIDAMIC AICD; 4-Hydroxyquinoline-3-carbonitrile; 3-cyano-4-quinolone; 4-Hydroxy-3-quinolinecarbonitrile; CHELIDAMIC ACID HYDRATE; 3-Quinolinecarbonitrile, 4-hydroxy-; Chelidamaic acid; Chelidamic aicd; Ammox-chelidonic acid; chelidamic acid approx.; 4-oxo-1,4-dihydroquinoline-3-carbonitrile; 1,4-Dihydro-4-oxo-3-quinolinecarbonitrile

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 389.3±27.0 °C at 760 mmHg
• 分子式: C₁₀H₆N₂O
• 分子量: 170.167
• 闪点: 189.2±23.7 °C
• 精确质量: 170.048019
• PSA: 56.65000
• LogP: 2.63
• 蒸汽压: 0.0±0.9 mmHg at 25°C
• 折射率: 1.702
• 储存条件: 2-8°C， 干燥

合成路线

113290-32-7 ~% 71083-59-5

文献：American Cyanamid Company Patent: US6384051 B1, 2002 ;

113290-32-7 75-05-8 ~% 71083-59-5

文献：Wyeth Holdings Corporation Patent: EP973746 B1, 2003 ; Location in patent: Page/Page column 41 ; EP 0973746 B1

2305-54-6 ~67% 71083-59-5

文献：Cernuchova, Petra; Vo-Thanh, Giang; Milata, Viktor; Loupy, Andre Heterocycles, 2004 , vol. 64, p. 177 - 191

94-05-3 ~% 71083-59-5 93560-70-4

文献：Lilly Industries Limited Patent: US4390541 A1, 1983 ;

20428-58-4 113290-32-7 ~% 71083-59-5

文献：Zhang, Nan; Wu, Biqi; Powell, Dennis; Wissner, Allan; B. Floyd, Middleton; D. Kovacs, Eleonora; Toral-Barza, Lourdes; Kohler, Constance Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 24 p. 2825 - 2828

134-20-3 ~% 71083-59-5

文献：Zhang, Nan; Wu, Biqi; Powell, Dennis; Wissner, Allan; B. Floyd, Middleton; D. Kovacs, Eleonora; Toral-Barza, Lourdes; Kohler, Constance Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 24 p. 2825 - 2828

74497-02-2 ~% 71083-59-5

文献：Cernuchova, Petra; Vo-Thanh, Giang; Milata, Viktor; Loupy, Andre Heterocycles, 2004 , vol. 64, p. 177 - 191

42466-67-1 74497-02-2 ~% 71083-59-5

文献：Osornio, Yazmin M.; Miranda, Luis D.; Cruz-Almanza, Raymundo; Muchowski, Joseph M. Tetrahedron Letters, 2004 , vol. 45, # 13 p. 2855 - 2858

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