278790-00-4

• 常用中文名：(R)-N-1-BOC-4-CBZ-2-哌嗪羧酸甲酯
• 常用英文名：(R)-N-1-BOC-4-CBZ-2-PIPERAZINECARBOXYLIC ACID METHYL ESTER
• CAS号：278790-00-4
• 分子式：C₁₉H₂₆N₂O₆
• 分子量：378.42000
• 发布时间：2018-12-20 16:03:27
• 更新时间：2024-01-04 16:43:34

名称

• 中文名: (R)-N-1-BOC-4-CBZ-2-哌嗪羧酸甲酯
• 英文名: 4-O-benzyl 1-O-tert-butyl 2-O-methyl (2R)-piperazine-1,2,4-tricarboxylate
• 英文别名: (r)-n-1-boc-4-cbz-2-piperazinecarboxylic acid methyl ester; (R)-4-Benzyl 1-tert-butyl 2-methyl piperazine-1,2,4-tricarboxylate

物化性质

• 分子式: C₁₉H₂₆N₂O₆
• 分子量: 378.42000
• 精确质量: 378.17900
• PSA: 85.38000
• LogP: 2.29330

安全

• 海关编码: 2933599090

合成路线

74-88-4 138775-02-7 ~64% 278790-00-4

文献：SCHERING CORPORATION Patent: WO2006/65828 A2, 2006 ; Location in patent: Page/Page column 90 ; WO 2006/065828 A2

126330-92-5 ~% 278790-00-4

文献：Hoekstra, William J.; Maryanoff, Bruce E.; Damiano, Bruce P.; Andrade-Gordon, Patricia; Cohen, Judith H.; Costanzo, Michael J.; Haertlein, Barbara J.; Hecker, Leonard R.; Hulshizer, Becky L.; Kauffman, Jack A.; Keane, Patricia; McComsey, David F.; Mitchell, John A.; Scott, Lorraine; Shah, Rekha D.; Yabut, Stephen C. Journal of Medicinal Chemistry, 1999 , vol. 42, # 25 p. 5254 - 5265

501-53-1 ~% 278790-00-4

文献：Hoekstra, William J.; Maryanoff, Bruce E.; Damiano, Bruce P.; Andrade-Gordon, Patricia; Cohen, Judith H.; Costanzo, Michael J.; Haertlein, Barbara J.; Hecker, Leonard R.; Hulshizer, Becky L.; Kauffman, Jack A.; Keane, Patricia; McComsey, David F.; Mitchell, John A.; Scott, Lorraine; Shah, Rekha D.; Yabut, Stephen C. Journal of Medicinal Chemistry, 1999 , vol. 42, # 25 p. 5254 - 5265

126330-91-4 ~% 278790-00-4

文献：Hoekstra, William J.; Maryanoff, Bruce E.; Damiano, Bruce P.; Andrade-Gordon, Patricia; Cohen, Judith H.; Costanzo, Michael J.; Haertlein, Barbara J.; Hecker, Leonard R.; Hulshizer, Becky L.; Kauffman, Jack A.; Keane, Patricia; McComsey, David F.; Mitchell, John A.; Scott, Lorraine; Shah, Rekha D.; Yabut, Stephen C. Journal of Medicinal Chemistry, 1999 , vol. 42, # 25 p. 5254 - 5265

24424-99-5 405175-79-3 ~% 278790-00-4

文献：Hoekstra, William J.; Maryanoff, Bruce E.; Damiano, Bruce P.; Andrade-Gordon, Patricia; Cohen, Judith H.; Costanzo, Michael J.; Haertlein, Barbara J.; Hecker, Leonard R.; Hulshizer, Becky L.; Kauffman, Jack A.; Keane, Patricia; McComsey, David F.; Mitchell, John A.; Scott, Lorraine; Shah, Rekha D.; Yabut, Stephen C. Journal of Medicinal Chemistry, 1999 , vol. 42, # 25 p. 5254 - 5265

上下游产品

上游产品  7
74-88-4 138775-02-7 126330-92-5 501-53-1
126330-91-4 24424-99-5 405175-79-3
下游产品  0

海关

海关编码	2933599090
中文概述	2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%