190728-25-7

• 常用中文名：6,7-二甲氧基-4-(4-氨基苯氧基)喹啉
• 常用英文名：4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline
• CAS号：190728-25-7
• 分子式：C₁₇H₁₆N₂O₃
• 分子量：296.320
• 发布时间：2019-01-02 09:34:51
• 更新时间：2026-07-02 09:17:42

名称

• 中文名: 6,7-二甲氧基-4-(4-氨基苯氧基)喹啉
• 英文名: 4-(6,7-dimethoxyquinolin-4-yl)oxyaniline
• 中文别名: 4-(6,7-二甲氧基喹啉-4-氧基)-苯胺; 卡博替尼中间体3; 4-羟基-6,21-二甲氧基喹啉; 4-[(6,7-二甲氧基喹啉-4-基)氧基]苯胺; 卡博替尼中间体3(4-[(6,7-二甲氧基喹啉-4-基)氧基]苯胺); 4-[(6,7-二甲氧基喹啉-4-基)氧]苯胺(卡博替尼中间体); 4-[(6,7-二甲氧基-4-喹啉基)氧基]苯胺; 卡博中间体(苯胺); 卡博替尼杂质4; 卡博替尼中间体 4-[(6,7-二甲氧基喹啉-4-基)氧基]苯胺; 4-[(6,7-二甲氧基喹啉-4-基)氧基]苯胺 4-((6,7-DIMETHOXYQUINOLIN-4-YL)OXY)ANILINE; 4-[(6,7-二甲氧基喹啉-4-基)氧基]苯胺 (卡博替尼中间体); 4-[(6,7-二甲氧基喹啉-4-基)氧基]苯胺 (卡博替尼杂质)
• 英文别名: 4-(4-Aminophenoxy)-6,7-dimethoxyquinoline; qc-2701; 4-(2,3-dimethoxynaphthalen-5-yloxy)benzenamine; [4-[(6,7-Dimethoxyquinolin-4-yl)oxy]phenyl]amine; 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline (Cabozantinib Impurity); 4-(6,7-dimethoxy quinolinoxy) aniline; Cabozantinib Impurity: 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline; 4-(6,7-dimethoxy quinoline-4-yloxy)phenylamine; 6,7-Dimethoxy-4-(4-aminophenyloxy)quinolone; Cabozantinib Genotoxic Impurity I; 4-[(6,7-dimethoxyquinolin-4-yl)oxy]aniline 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline; 4-(6,7-dimethoxyquinolin-4-yl)oxyaniline, 10 mM in DMSO; BenzeMine, 4-[(6,7-diMethoxy-4-quinolinyl)oxy]; Cabozantinib Amine Analog; 4-(6,7-Dimethoxy-quinoL; PDGFR-IN-2; 4-[(6,7-Dimethoxy-4-quinolinyl)oxy]aniline; 1-((6,7-dimethoxyquinolin-4-yl)oxy)aniline; 190-74-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline; BenzenaMine, 4-[(6,7-diMethoxy-4-quinolinyl)oxy]; 4-[(6,7-diMethoxy-4-quinolinyl)oxy]-BenzenaMine; 4-[(6,7-dimethoxy-4-quinolinyl)oxy]; Benzenam; 4-[(6,7-Dimethoxy-4-quinolyl)oxy]aniline; Intermediate 1 of Cabozantinib; 6,7-Dimethoxy-4-(4-aminophenoxy)quinoline

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 481.8±45.0 °C at 760 mmHg
• 熔点: 214 °C
• 分子式: C₁₇H₁₆N₂O₃
• 分子量: 296.320
• 闪点: 245.2±28.7 °C
• 精确质量: 296.116089
• PSA: 66.60000
• LogP: 2.83
• 外观性状: 固体;Light yellow to Brown powder to crystal
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.646
• 储存条件: 室温，干燥

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933499090

合成路线

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海关

海关编码	2933499090
中文概述	2933499090. 其他含喹琳或异喹啉环系的化合物〔但未进一步稠合的〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%