129970-98-5

• 常用中文名：(S)-2-((3S,5aS,9aS,10aS)-3-甲基-1,4-二氧十氢吡嗪并[1,2-a]吲哚-2(1H)-基)戊酸乙酯 (培哚普利杂质)
• 常用英文名：Perindopril Diketopiperazine
• CAS号：129970-98-5
• 分子式：C₁₉H₃₀N₂O₄
• 分子量：350.45300
• 发布时间：2016-03-19 04:42:19
• 更新时间：2026-07-16 23:17:43

名称

• 中文名: (S)-2-((3S,5AS,9AS,10AS)-3-甲基-1,4-二氧十氢吡嗪并[1,2-A]吲哚-2(1H)-基)戊酸乙酯
• 英文名: ethyl (2S)-2-[(3S,5aS,9aS,10aS)-3-methyl-1,4-dioxo-5a,6,7,8,9,9a,10,10a-octahydro-3H-pyrazino[1,2-a]indol-2-yl]pentanoate
• 中文别名: 培哚普利杂质6(培哚普利杂质F); 培哚普利 相关物质F; 培哚普利杂质F; 培哚普利杂质CAS号:129-5; 培哚普利相关物质F 标准品; 培哚普利相关化合物F; 培哚普利杂质06; 培哚普利杂质 F; 叔丁胺培哚普利杂质F; (S)-2-((3S,5AS,9AS,10AS)-3-甲基-1,4-二氧十氢吡嗪并[1,2-A]吲哚-2(1H)-基)戊酸乙酯 (培哚普利杂质); 培哚普利二酮哌嗪
• 英文别名: Perindoprilat impurity F; ETHYL QUINOLINE-2-ACETATE; Perindopril Related Compound F; Perindopril Related Compound F ((S)-ethyl 2-{(3S,5aS,9aS,10aS)-3-methyl-1,4-dioxodecahydropyrazino[; (S)-Ethyl 2-((3S,5aS,9aS,10aS)-3-methyl-1,4-dioxodecahydropyrazino[1,2-a]indol-2(1H)-yl)pentanoate; 2-quinolineacetic acid ethyl ester; Perindopril Related Compound F (10 mg) ((S)-ethyl 2-{(3S,5aS,9aS,10aS)-3-methyl-1,4-dioxodecahydropyrazino[1,2-a]indol-2(1H)-yl}pentanoate); Perindopril IMpurity – F; Perindopril Impurity 6; [3S-[2(R*),3α,5aβ,9aβ,10aβ]]; Perindopril tert-Butylamine Impurity F; (alphaS,3S,5aS,9aS,10aS)-Decahydro-3-methyl-1,4-dioxo-alpha-propylpyrazino[1,2-a]indole-2(1H)-acetic acid ethyl ester; (S)-Ethyl 2-((3S,5aS,9aS,10aS)-3-methyl-1,4-dioxodecahydropyrazino[1,2-a]indol-2(1H)-yl)pentanoate (Perindopril Impurity); Perindopril Impurity F/ Perindopril Related Compound F (Perindopril Diketopiperazine); (αS,3S,5aS,9aS,10aS)-Decahydro-3-Methyl-1,4-dioxo-α-propylpyrazino[1,2-a]indole-2(1H)-acetic Acid Ethyl Ester; Perindopril Impurity F (Perindopril Related Compound F); Perindopril Related CoMpound F; Perindopril IMpurity F; Pyrazino[1,2-a]indole-2(1H)-acetic acid, decahydro-3-methyl-1,4-dioxo-α-propyl-, ethyl ester, (αS,3S,5aS,9aS,10aS); Perindoprilat impurity 6; quinolin-2-yl-acetic acid ethyl ester; (S)-Ethyl 2-{(3S,5aS,9aS,10aS)-3-methyl-1,4-dioxodecahydropyrazino[1,2-a]indol-2(1H)-yl}pentanoate; ethyl 2-quinolineacetate; diketopiperazine; Perindopril Impurity 6(Perindopril Impurity F )

物化性质

• 密度: 1.17±0.1 g/cm3
• 分子式: C₁₉H₃₀N₂O₄
• 分子量: 350.45300
• 精确质量: 350.22100
• PSA: 66.92000
• LogP: 1.98440
• 储存条件: 室温
• 水溶解性: Very slightly soluble (0.12 g/L) (25 ºC)

安全

• 危险品运输编码: NONH for all modes of transport

合成路线

107133-36-8 ~0% 129970-98-5 95153-31-4

文献：WO2007/58634 A1, ; Page/Page column 17-19 ;

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