14318-66-2

• 常用中文名：N-甲基-3-甲氧基苯胺
• 常用英文名：3-Methoxy-N-methylaniline
• CAS号：14318-66-2
• 分子式：C₈H₁₁NO
• 分子量：137.179
• 发布时间：2018-07-01 20:24:12
• 更新时间：2024-01-02 17:51:32
• 下载msds

名称

• 中文名: N-甲基-3-甲氧基苯胺
• 英文名: 3-Methoxy-N-methylaniline
• 中文别名: 3-甲氧基-N-甲基苯胺; N-甲基-间茴香胺
• 英文别名: EINECS 238-259-9; MFCD05665953; 3-Methoxy-N-methylaniline; Benzenamine, 3-methoxy-N-methyl-

物化性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 238.8±23.0 °C at 760 mmHg
• 分子式: C₈H₁₁NO
• 分子量: 137.179
• 闪点: 88.7±12.1 °C
• 精确质量: 137.084061
• PSA: 21.26000
• LogP: 1.31
• 外观性状: 棕色液体
• 蒸汽压: 0.0±0.5 mmHg at 25°C
• 折射率: 1.553
• 储存条件:

  贮存于阴凉处。保持容器密闭在干燥和通风良好的地方。

• 分子结构:

  1、摩尔折射率：42.54; 2、 摩尔体积（cm³/mol）：132.8; 3、 等张比容（90.2K）：322.8; 4、 表面张力（dyne/cm）：34.8; 5、 极化率：16.86; 6、 介电常数：未确定

• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:1

  3.氢键受体数量:2

  4.可旋转化学键数量:2

  5.互变异构体数量:无

  6.拓扑分子极性表面积21.3

  7.重原子数量:10

  8.表面电荷:0

  9.复杂度:95.3

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

• 更多:

  1．性状：不可用

  2．密度（g/mL,25/4℃）：1.049

  3．相对蒸汽密度（g/mL,空气=1）：不可用

  4．熔点（ºC）：不可用

  5．沸点（ºC,常压）：239-240

  6．沸点（ºC,5.2kPa）：不可用

  7．折射率：1.5690

  8．闪点（ºC）：不可用

  9．比旋光度（º）：不可用

  10．自燃点或引燃温度（ºC）：不可用

  11．蒸气压（kPa,25ºC）：不可用

  12．饱和蒸气压（kPa,60ºC）：不可用

  13．燃烧热（KJ/mol）：不可用

  14．临界温度（ºC）：不可用

  15．临界压力（KPa）：不可用

  16．油水（辛醇/水）分配系数的对数值：不可用

  17．爆炸上限（%,V/V）：不可用

  18．爆炸下限（%,V/V）：不可用

  19．溶解性：不可用

MSDS

Section1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE Product name: 3-Methoxy-N-methylaniline Section2. HAZARDS IDENTIFICATION Classification of the substance or mixture According to Regulation (EC) No1272/2008 Acute toxicity, Oral (Category 4) Eye irritation (Category 2) Skin sensitization (Category 1) According to European Directive 67/548/EEC as amended. May cause sensitization by skin contact. Harmful if swallowed. Label elements Pictogram Signal wordWarning Hazard statement(s) Harmful if swallowed. May cause an allergic skin reaction. Causes serious eye irritation. Precautionary statement(s) Wear protective gloves. P305 + P351 + P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Hazard symbol(s) XnHarmful R-phrase(s) R43May cause sensitization by skin contact. R22Harmful if swallowed. S-phrase(s) S37/39Wear suitable gloves and eye/face protection. Other hazards - none Section3. COMPOSITION/INFORMATION ON INGREDIENTS Synonyms: N-Methyl-m-anisidine Formula: C8H11NO Molecular Weight: 137,18 g/mol CAS-No.EC-No.Index-No.ClassificationConcentration N-Methyl-m-anisidine 14318-66-2238-259-9-Acute Tox. 4; Eye Irrit. 2; Skin - Sens. 1; H302, H317, H319 Xn, R43 - R22 For the full text of the H-Statements mentioned in this Section, see Section 16. Section4. FIRST AID MEASURES General advice Consult a physician. Show this safety data sheet to the doctor in attendance. If inhaled If breathed in, move person into fresh air. If not breathing give artificial respiration Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. Section5. FIRE-FIGHTING MEASURES Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Special protective equipment for fire-fighters Wear self contained breathing apparatus for fire fighting if necessary. Section6. ACCIDENTAL RELEASE MEASURES Personal precautions Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Environmental precautions Do not let product enter drains. Methods and materials for containment and cleaning up Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for disposal. Section7. HANDLING AND STORAGE Precautions for safe handling Avoid inhalation of vapour or mist. Normal measures for preventive fire protection. Conditions for safe storage Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Section8. EXPOSURE CONTROLS/PERSONAL PROTECTION Personal protective equipment Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Hand protection The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Handle with gloves. Eye protection Face shield and safety glasses Skin and body protection Choose body protection according to the amount and concentration of the dangerous substance at the work place. Hygiene measures Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Section9. PHYSICAL AND CHEMICAL PROPERTIES Appearance Formliquid Colourcolourless Safety data pH no data available Melting pointno data available Boiling point239 - 240 °C - lit. Flash point> 110 °C - closed cup Ignition temperature no data available Lower explosion limit no data available Upper explosion limit no data available Density1,049 g/cm3 at 25 °C Water solubilityno data available Partition coefficient: log Pow: 1,698 n-octanol/water Section10. STABILITY AND REACTIVITY Chemical stability Stable under recommended storage conditions. Conditions to avoid no data available Materials to avoid Strong oxidizing agents Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides, nitrogen oxides (NOx) Section11. TOXICOLOGICAL INFORMATION Acute toxicity no data available Skin corrosion/irritation Serious eye damage/eye irritation no data available Respiratory or skin sensitization May cause allergic skin reaction. Germ cell mutagenicity no data available Carcinogenicity IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. Reproductive toxicity no data available Specific target organ toxicity - single exposure no data available Specific target organ toxicity - repeated exposure no data available Aspiration hazard no data available Potential health effects InhalationMay be harmful if inhaled. May cause respiratory tract irritation. IngestionHarmful if swallowed. SkinMay be harmful if absorbed through skin. May cause skin irritation. EyesMay cause eye irritation. Signs and Symptoms of Exposure To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. Additional Information RTECS: no data available Section12. ECOLOGICAL INFORMATION Toxicity no data available Persistence and degradability no data available Bioaccumulative potential no data available Mobility in soil no data available PBT and vPvB assessment no data available Other adverse effects no data available Section13. DISPOSAL CONSIDERATIONS Product Observe all federal, state, and local environmental regulations. Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Contaminated packaging Dispose of as unused product. Section14. TRANSPORT INFORMATION ADR/RID Not dangerous goods IMDG Not dangerous goods IATA Not dangerous goods Section15. REGULATORY INFORMATION SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

毒理学数据: 急性毒性：不可用。 生态学数据: 1、其它有害作用：该物质对环境可能有危害，对水体应给予特别注意。

安全

• 符号: GHS07
• 信号词: Warning
• 危害声明: H302-H317
• 警示性声明: P280
• 个人防护装备: Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
• 危害码 (欧洲): Xn:Harmful;
• 风险声明 (欧洲): R22;R43
• 安全声明 (欧洲): S24-S36/37
• 危险品运输编码: NONH for all modes of transport
• 海关编码: 2922299090

合成路线

海关

海关编码	2922299090
中文概述	2922299090. 其他氨基(萘酚、酚)及醚、酯〔包括它们的盐, 但含有一种以上含氧基的除外〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
Summary	2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%