25252-46-4

25252-46-4结构式

常用中文名：1,3-二甲基-1H-噻吩并[2,3-c]吡唑-5-羧酸
常用英文名：1,3-DIMETHYL-1H-THIENO[2,3-C]PYRAZOLE-5-CARBOXYLIC ACID
CAS号：25252-46-4
分子式：C₈H₈N₂O₂S
分子量：196.22600
发布时间：2018-12-25 12:17:06
更新时间：2024-01-05 09:32:17

中文名	1,3-二甲基-1H-噻吩并[2,3-c]吡唑-5-羧酸
英文名	1,3-dimethylthieno[2,3-c]pyrazole-5-carboxylic acid
中文别名	1,3-二甲基-1H-噻吩基[2,3-c!吡唑-5-羧酸 1,3-二甲基-1H-噻吩[2,3-C]吡唑-5-甲酸
英文别名	1,3-dimethyl-1H-thieno[2,3-c]pyrazole-5-carboxylic acid 1,3-Dimethyl-thieno<2.3-c>pyrazol-5-carbonsaeure MFCD00126746

密度	1.54g/cm3
沸点	401.5ºC at 760mmHg
熔点	316-317ºC
分子式	C₈H₈N₂O₂S
分子量	196.22600
闪点	196.6ºC
精确质量	196.03100
PSA	83.36000
LogP	1.64140
蒸汽压	3.63E-07mmHg at 25°C
折射率	1.724
储存条件	室温，干燥
分子结构	1、摩尔折射率：47.26 2、摩尔体积（cm³/mol）：128.7 3、等张比容（90.2K）：342.4 4、表面张力（dyne/cm）：50.0 5、极化率（10-24cm3）：18.73
计算化学	1.疏水参数计算参考值（XlogP）:1.8 2.氢键供体数量:1 3.氢键受体数量:4 4.可旋转化学键数量:1 5.互变异构体数量:无 6.拓扑分子极性表面积83.4 7.重原子数量:13 8.表面电荷:0 9.复杂度:236 10.同位素原子数量:0 11.确定原子立构中心数量:0 12.不确定原子立构中心数量:0 13.确定化学键立构中心数量:0 14.不确定化学键立构中心数量:0 15.共价键单元数量:1
更多	1. 熔点（ºC）：316~317

Name:	1 3-Dimethyl-1h-thieno[2 3-c]pyrazole-5-carboxylic acid 95+% Material Safety Data Sheet
Synonym:
CAS:	25252-46-4

Section 1 - Chemical Product MSDS Name:1 3-Dimethyl-1h-thieno[2 3-c]pyrazole-5-carboxylic acid 95+% Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
25252-46-4	1,3-Dimethyl-1H-thieno[2,3-c]pyrazole-	95+%	unlisted

Hazard Symbols: XI
Risk Phrases: 36/37/38

Section 3 - HAZARDS IDENTIFICATION

EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 25252-46-4: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: brown
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 316 - 317 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C8H8N2O2S
Molecular Weight: 196.23

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 25252-46-4 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
1,3-Dimethyl-1H-thieno[2,3-c]pyrazole-5-carboxylic acid - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION

Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
WGK (Water Danger/Protection)
CAS# 25252-46-4: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 25252-46-4 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 25252-46-4 is not listed on the TSCA inventory.
It is for research and development use only.

SECTION 16 - ADDITIONAL INFORMATION
N/A

危害码 (欧洲)	Xi: Irritant;
风险声明 (欧洲)	R36/37/38
海关编码	2934999090

68-11-1

27006-76-4

25252-46-4

文献：Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 5, p. 567 Khimiya Geterotsiklicheskikh Soedinenii, , vol. 5, # 4 p. 760 - 761

50880-19-8

25252-46-4

文献：Journal of Organic Chemistry USSR (English Translation), , vol. 9, p. 2216 - 2218 Zhurnal Organicheskoi Khimii, , vol. 9, p. 2201 - 2204

50734-86-6

25252-46-4

文献：Journal of Organic Chemistry USSR (English Translation), , vol. 9, p. 2216 - 2218 Zhurnal Organicheskoi Khimii, , vol. 9, p. 2201 - 2204

上游产品 4
68-11-1 27006-76-4 50880-19-8 50734-86-6
下游产品 0

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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