28910-89-6

• 常用中文名：2-(2-乙酰肼基)-7-氯-5-苯基-2H-1,4-苯并二氮杂卓
• 常用英文名：2-(2-Acethydrazide)-7-chloro-5-phenyl-2H-1,4-dibenzodiazopine-2-one
• CAS号：28910-89-6
• 分子式：C₁₇H₁₅ClN₄O
• 分子量：326.78000
• 发布时间：2018-12-26 16:10:12
• 更新时间：2025-08-21 11:52:34

名称

• 中文名: 2-(2-乙酰肼基)-7-氯-5-苯基-2H-1,4-苯并二氮杂卓
• 英文名: N'-(7-chloro-5-phenyl-3H-1,4-benzodiazepin-2-yl)acetohydrazide
• 中文别名: 2-(2-乙酰基肼基)-7-氯-5-苯基-3H-1,4-苯并二氮杂卓; N'-(7-氯-5-苯基-3H-苯并[E][1,4]二氮杂卓-2-基)乙酰甲酰肼; 阿普唑仑杂质18; 阿普唑仑杂质A; 2-(2-乙酰肼基)-7-氯-5-苯基-3H-1,4-苯并二氮杂质; N'-(7-氯-5-苯基-3H-苯并[E][1,4]二氮杂卓-2-基)乙酰肼; 2-(2-乙酰基肼基)-7-氯-5-苯基L-3H-1,4-苯(并)二氮; 阿普唑仑相关化合物A; APZL杂质2
• 英文别名: N,-(7-chloro-5-phenyl-3H-benzo[e][1,4]diazin-2-yl)acetohydrazide; Acetic acid [7-chloro-5-phenyl-1,3; 2-(2-ACETYLHYDRAZINO)-7-CHLORO-5-PHENYL-3H-1,4-BENZODIAZINE; N'-(7-chloro-5-phenyl-3H-1,4-benzodiazin-2-yl)acetohydrazide; 7-chloro-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one acetylhydrazone; 2-(2-ACETYLTHYDRAZINA)-7-CHLORO-5-PHENYL-3H-1,4-BENZODIAZAPINE; AlprazolaM Related CoMpound A; Alprazolam Impurity 18; 7-Chloro-1,3-Dihydro-5-Phenyl-2H-1,4-Benzodiazine-2-Thione; 7-Chloro-5-phenyl-1,3-dihydro-benzo[e][1,4]diazine-2-thion; ACETIC ACID [7-CHLORO-5-PHENYL-1,3-DIHYDRO-BENZO[E][1,4]DIAZIN-(2E)-YLIDENE]-HYDRAZIDE; Alprazolam Related Compound A (2-(2-acetylhydrazino)-7-chloro-5-phenyl-3H-1,4-benzodiazine); ACETIC ACID, 2-(7-CHLORO-5-PHENYL-3H-1,4-BENZODIAZIN-2-YL)HYDRAZIDE; 7-Chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazine-2 acetylhydrazone; 2-(2-ACETYLHYDRAZINA)-7-CHLORO-5-PHENYL-3H-1,4-BENZODIAZAPINE; 7-Chloro-5-phenyl-1,3-dihydro-benzo[e][1,4]diazine-2-thione; 7-Chloro-5-phenyl-3H-2-(2-acetylthydrazina)-1,4-benzodiazapine; Alprazolam Related Compound A (30 mg) (2-(2-acetylhydrazino)-7-chloro-5-phenyl-3H-1,4-benzodiazine); 7-Chloro-1,3-Dihydro-5-Phenyl-2H-1,4-Benzodiazine-2-One; Essigsaeure-2-(7-Chlor-5-phenyl-3H-1,4-benzodiazepin-2-yl)hydrazid; n'-(7-Chloro-5-phenyl-3h-benzo[e][1,4]diazin-2-yl)acetohydrazide; 7-Chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepine-2 acetylhydrazone; Alprazolam Related Compound A; dihydro-benzo[e][1,4]diazepin-(2E); 2-(2-Acet-Hydrazide)-7-Chloro-5-Phenyl-2h-1,4-Dibenzodiazopine-2-One; 2-[7-CHLORO-5-PHENYL-3H-1,4-BENZODIAZIN-2YL]-ACETYL-HYDRAZIDE; 2-(2-acetylhydrazino)-7-chloro-5-phenyl-3H-1,4-benzodiazepine; Alprazolam Impurity A; ylidene]-hydrazide

物化性质

• 密度: 1.33g/cm3
• 熔点: 245-247ºC
• 分子式: C₁₇H₁₅ClN₄O
• 分子量: 326.78000
• 精确质量: 326.09300
• PSA: 79.84000
• LogP: 2.60590
• 外观性状: 固体
• 折射率: 1.661
• 储存条件: 室温

安全

• 危险品运输编码: NONH for all modes of transport

合成路线

18091-89-9 ~% 28910-89-6

文献：Takeda Chemical Industries, Ltd. Patent: US4116956 A1, 1978 ;

4547-02-8 ~% 28910-89-6

文献：The Upjohn Company Patent: US3987052 A1, 1976 ;

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