130525-62-1

• 常用中文名：扎那米韦中间体2
• 常用英文名：4-a-AMino-N-acetyl-2-deoxy-2,3-didehydro-D-neuraMinate
• CAS号：130525-62-1
• 分子式：C₁₁H₁₈N₂O₇
• 分子量：290.27000
• 发布时间：2018-05-10 08:00:00
• 更新时间：2026-07-27 00:17:14

名称

• 中文名: 扎那米韦中间体2
• 英文名: 4-a-Amino-N-acetyl-2-deoxy-2,3-didehydro-D-neuraminate
• 中文别名: 扎那米韦胺; 扎那米韦杂质3(扎那米韦杂质C); 2,3-二脱氢-4-氨基-N-乙酰; 扎那米韦中间体DN-1; 扎那米韦杂质2; 扎那米韦中间体 A; 扎那米韦杂质C; 氨基扎那米韦; 2,3-二脱氢-4-氨基-N-乙酰神经氨酸
• 英文别名: Zanamivir Impurity C; Zanamivir intermediates A; 4-alpha-Amino-N-acetyl-2-deoxy-2,3-didehydro-D-neuraminate; 4-amino-4-deoxy-Neu5Ac2en; Zanamivir Amine; 4-amino-2-deoxy-2,3-didehydro-N-acetylneuraminic acid; Zanamivir Impurity 3(Zanamivir Impurity C); (4S,5R,6R)-5-ACETAMIDO-4-AMINO-6-[(1R,2R)-1,2,3-TRIHYDROXYPROPYL]-5,6-DIHYDROPYRAN-2-CBOXYLIC ACID; acetamido-4-ammonio-2,3,4,5-tetradeoxy-D-glycero-D-galacto-2-nonulopyranosidonate; "4-α-Amino-N-acetyl-2-deoxy-2,3-didehydro-D-neuraminate"; D-glycero-D-galacto-Non-2-enonic acid, 5-(acetylamino)-4-amino-2,6-anhydro-3,4,5-trideoxy; Zanamivir Impurity 2; 5-acetamido-4-amino-2,6-anhydro-3,4,5-trideoxy-D-glycero-D-galacto-non-2-enonic acid; (4S,5R,6R)-5-ACETAMIDO-4-AMINO-6-[(1R,2R)-1,2,3-TRIHYDROXYPROPYL]-5,6-DIHYDROPYRAN-2-CARBOXYLIC ACID; 4-AM-DANA; Zanamivir intermediate DN-1; (2R,3R,4S)-3-(Acetylamino)-4-[(thien-2-ylsulfoyl)amino]-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid; 5-(Acetylamino)-4-amino-2,6-anhydro-3,4,5-trideoxy-D-glycero-D-galactonon-2-enonic acid; 5-(Acetylamino)-4-amino-2,6-anhydro-3,4,5-trideoxy-D-glycero-D-galacto-non-2-enonic acid

物化性质

• 密度: 1.53g/cm3
• 沸点: 734.5ºC at 760mmHg
• 分子式: C₁₁H₁₈N₂O₇
• 分子量: 290.27000
• 闪点: 398ºC
• 精确质量: 290.11100
• PSA: 162.34000
• 蒸汽压: 6.64E-25mmHg at 25°C
• 折射率: 1.611

合成路线

130525-58-5 ~% 130525-62-1

文献：Carbohydrate Research, , vol. 259, # 2 p. 301 - 305

152178-79-5 ~54% 130525-62-1

文献：Chandler, Malcolm; Bamford, Mark J.; Conroy, Richard; Lamont, Brian; Patel, Bina; et al. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 9 p. 1173 - 1180

130525-63-2 ~94% 130525-62-1

文献：Schreiner, Erwin; Zbiral, Erich; Kleineidam, Reinhard G.; Schauer, Roland Liebigs Annalen der Chemie, 1991 , # 2 p. 129 - 134

139110-70-6 ~% 130525-62-1

文献：Carbohydrate Research, , vol. 259, # 2 p. 301 - 305

108740-39-2 ~% 130525-62-1

文献：Journal of the American Chemical Society, , vol. 135, # 36 p. 13254 - 13257

78850-37-0 ~% 130525-62-1

文献：Journal of the American Chemical Society, , vol. 135, # 36 p. 13254 - 13257

1453411-75-0 ~65% 130525-62-1

文献：Shidmoossavee, Fahimeh S.; Watson, Jacqueline N.; Bennet, Andrew J. Journal of the American Chemical Society, 2013 , vol. 135, # 36 p. 13254 - 13257

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