23611-75-8

• 常用中文名：6-氯-2-乙酰基吡嗪
• 常用英文名：Methyl 6-chloropyrazine-2-carboxylate
• CAS号：23611-75-8
• 分子式：C₆H₅ClN₂O₂
• 分子量：172.569
• 相关类别： 医药中间体 杂环化合物 吡嗪类化合物
• 发布时间：2018-02-09 08:00:00
• 更新时间：2026-07-22 12:58:04

名称

• 中文名: 6-氯-2-吡嗪甲酸甲酯
• 英文名: methyl 6-chloropyrazine-2-carboxylate
• 中文别名: 6-氯吡嗪-2-羧酸甲酯; 6-氯-2-吡嗪羧酸甲酯; 6-氯-2-甲酸甲酯吡嗪; 甲基 6-氯吡嗪-2-甲酸基酯; 2-氯-6-吡嗪羧酸甲酯; 6-氯吡嗪-2-甲酸 甲酯; 2-氯吡嗪-6-羧酸甲酯; 6-氯哌嗪-2-羧酸甲酯; 6- 氯-2-乙酰基吡嗪; 6-氯-2-羧酸甲酯吡嗪; 6-氯-2-吡嗪甲酸甲酯/ 6-氯-2-乙酰基吡嗪; 6-氯吡嗪-2-甲酸甲酯
• 英文别名: 6-Chloropyrazine-2-cboxylic acid methyl ester; 2-chloro-6-CO2ME-pyrazine; 6-Chloro-pyrazine-2-carboxylicacidmethylester; 6-chloro-2-methoxycarbonylpyrazine; Methyl 6-chloro-2-pyrazinecarboxylate; 6-Chloro-pyrazine-2-cbo; 2-Chloro-6-pyrazinecarboxylic acid methyl ester; m90108; methyl-5-chloropyrazine-2-carboxylate; Methyl 2-chloropyrazine-6-cboxylate; 2-Pyrazinecarboxylic acid, 6-chloro-, methyl ester; methyl 6-chloro-2-pyrazinecboxylate(SALTDATA: FREE); 6-Chloro-pyrazine-2-cboxylic acid methyl ester, min; 6-chloro-2-Pyrazinecboxylic acid methyl ester; Methyl6-chloropyrazine-2-cboxylate; METHYL 6-CHLOROPYRAZINE-2-CBOXYLATEMETHYL 6-CHLOROPYRAZINE-2-CBOXYLATE; 6-Chloro-pyrazine-2-c; 2-Pyrazinecboxylic acid, 6-chloro-, methyl ester; 2-Pyrazinecarboxylic acid,6-chloro-,methyl ester; Methyl 6-chloropyrazine-2-cboxylate; 2-Chloro-6-pyrazinecboxylic acid methyl ester; 2-Chloro-6-pyrazinecboxylic acid methyl ester ISO 9001：2015 REACH; METHYL 6-CHLORO-2-PYRAZINECBOXYLATE; ethyl 6-chloropyrazine-2-cboxylate; 6-Chloro-pyrazine -2-cboxylate

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 256.4±35.0 °C at 760 mmHg
• 熔点: 40-41 °C
• 分子式: C₆H₅ClN₂O₂
• 分子量: 172.569
• 闪点: 108.9±25.9 °C
• 精确质量: 172.003952
• PSA: 52.08000
• LogP: 0.66
• 外观性状: Solid
• 蒸汽压: 0.0±0.5 mmHg at 25°C
• 折射率: 1.534
• 储存条件: 2-8°C， 惰性气体

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933990090

合成路线

770-00-3 ~67% 23611-75-8

文献：Scanio, Marc J. C.; Shi, Lei; Bunnelle, William H.; Anderson, David J.; Helfrich, Rosalind J.; Malysz, John; Thorin-Hagene, Kirsten K.; Van Handel, Ceclia E.; Marsh, Kennan C.; Lee, Chih-Hung; Gopalakrishnan, Murali Journal of Medicinal Chemistry, 2011 , vol. 54, # 21 p. 7678 - 7692

6164-79-0 ~72% 23611-75-8

文献：Matthews, Hayden; Ranson, Marie; Tyndall, Joel D.A.; Kelso, Michael J. Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 22 p. 6760 - 6766

85661-24-1 ~% 27825-21-4 23611-75-8

文献：Journal of Chemical Research, Miniprint, , # 10 p. 2860 - 2875

770-00-3 ~% 27825-21-4 23611-75-8 33332-25-1

文献：Journal of Heterocyclic Chemistry, , vol. 31, # 5 p. 1177 - 1180

上下游产品

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770-00-3 6164-79-0 85661-24-1
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海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%