54025-36-4

• 常用中文名：Estr-4-en-3-one,17-[[[(2-chloroethyl)nitrosoamino]carbonyl]oxy]-, (17b)- (9CI)
• 常用英文名：Estr-4-en-3-one,17-[[[(2-chloroethyl)nitrosoamino]carbonyl]oxy]-, (17b)- (9CI)
• CAS号：54025-36-4
• 分子式：C₂₁H₂₉ClN₂O₄
• 分子量：408.91900
• 发布时间：2016-02-11 19:52:20
• 更新时间：2024-04-01 22:36:51

名称

• 英文名: Estr-4-en-3-one, 17-[[[(2-chloroethyl)nitrosoamino]carbonyl]oxy]-, (17.β.)
• 英文别名: 19-nortestosterone nitrosocarbamate

物化性质

• 密度: 1.43g/cm3
• 沸点: 529.4ºC at 760mmHg
• 分子式: C₂₁H₂₉ClN₂O₄
• 分子量: 408.91900
• 闪点: 274ºC
• 精确质量: 408.18200
• PSA: 76.04000
• LogP: 4.85560
• 折射率: 1.661

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : KG7962400 CHEMICAL NAME : Estr-4-en-3-one, 17-((((2-chloroethyl)nitrosoamino)carbonyl)oxy)-, (17-beta)- CAS REGISTRY NUMBER : 54025-36-4 LAST UPDATED : 198602 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C21-H29-Cl-N2-O4 MOLECULAR WEIGHT : 408.97 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2190 mg/kg TOXIC EFFECTS : Gastrointestinal - gastritis Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 49,290,1981 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 155 mg/kg TOXIC EFFECTS : Gastrointestinal - gastritis Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 49,290,1981 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 4 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - acute pulmonary edema Gastrointestinal - gastritis Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 49,290,1981 TYPE OF TEST : LD10 - Lethal Dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1630 mg/kg TOXIC EFFECTS : Gastrointestinal - ulceration or bleeding from stomach Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 49,290,1981 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 98 mg/kg TOXIC EFFECTS : Gastrointestinal - peritonitis Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 49,290,1981 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 8 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - acute pulmonary edema Gastrointestinal - gastritis Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 49,290,1981