548-40-3

• 常用中文名：尖刺檗鹼
• 常用英文名：2H-1,24:12,15-Dietheno-6,10-metheno-16H-pyrido[2',3':17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinolin-9-ol,3,4,4a,5,16a,17,18,19-octahydro-21,22,26-trimethoxy-4,17-dimethyl-, (4aR,16aS)-
• CAS号：548-40-3
• 分子式：C₃₇H₄₀N₂O₆
• 分子量：608.72300
• 发布时间：2018-05-08 08:00:00
• 更新时间：2024-02-02 12:02:53

名称

• 中文名: 尖刺檗鹼
• 英文名: oxyacanthine
• 英文别名: Oxyacanthine; Oxyacanthin; vinetine; 6,7,6'-trimethoxy-2,2'-dimethyl-oxyacanthan-12'-ol; 6,6',7-Trimethoxy-2,2'-dimethyloxyacanthan-12'-ol; Oxyacanthan-12'-ol, 6,6',7'-trimethoxy-2,2'-dimethyl-; Oxycanthine

物化性质

• 密度: 1.204g/cm3
• 沸点: 707ºC at 760mmHg
• 分子式: C₃₇H₄₀N₂O₆
• 分子量: 608.72300
• 闪点: 381.4ºC
• 精确质量: 608.28900
• PSA: 72.86000
• LogP: 6.73520
• 折射率: 1.601

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : RR6475000 CHEMICAL NAME : Oxyacanthan-12'-ol, 6,6',7-trimethoxy-2,2'-dimethyl- CAS REGISTRY NUMBER : 548-40-3 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C37-H40-N2-O6 MOLECULAR WEIGHT : 608.79 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 250 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,17,1953 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 50 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 24,2413,1976

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