5688-80-2

• 常用中文名：UNII:B6B7TX22VO
• 常用英文名：UNII:B6B7TX22VO
• CAS号：5688-80-2
• 分子式：C₁₂H₂₀ClNO₃
• 分子量：261.745
• 发布时间：2016-09-14 05:07:05
• 更新时间：2024-01-30 21:53:44
• 3,4,5-Trimethoxyamphetamine (TMA), is a psychedelic hallucinogen that has appeared on the illicit drug market.

名称

• 英文名: 1-(3,4,5-trimethoxyphenyl)propan-2-amine,hydrochloride
• 英文别名: Phenethylamine, 3,4,5-trimethoxy-α-methyl-, hydrochloride (8CI); Benzeneethanamine, 3,4,5-trimethoxy-α-methyl-, hydrochloride (9CI); Benzeneethanamine, 3,4,5-trimethoxy-α-methyl-, hydrochloride; 1-(3,4,5-Trimethoxyphenyl)propan-2-amine hydrochloride (1:1); Phenethylamine, 3,4,5-trimethoxy-α-methyl-, hydrochloride; Phenethylamine, α-methyl-3,4,5-trimethoxy-, hydrochloride; Benzeneethanamine, 3,4,5-trimethoxy-α-methyl-, hydrochloride (1:1); 1-(3,4,5-Trimethoxyphenyl)-2-propanamine hydrochloride (1:1); UNII:B6B7TX22VO

物化性质

• 密度: 1.048g/cm3
• 沸点: 321.7ºC at 760 mmHg
• 分子式: C₁₂H₂₀ClNO₃
• 分子量: 261.745
• 闪点: 148.6ºC
• 精确质量: 261.113159
• PSA: 53.71000
• LogP: 3.10440
• 储存条件: -20°C，密闭，干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : SI2285000 CHEMICAL NAME : Phenethylamine, alpha-methyl-3,4,5-trimethoxy-, hydrochloride CAS REGISTRY NUMBER : 5688-80-2 LAST UPDATED : 198910 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C12-H19-N-O3.Cl-H MOLECULAR WEIGHT : 261.78 WISWESSER LINE NOTATION : Z1Y1&R CO1 DO1 EO1 &GH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - man DOSE/DURATION : 880 ug/kg TOXIC EFFECTS : Behavioral - hallucinations, distorted perceptions Behavioral - changes in motor activity (specific assay) Gastrointestinal - nausea or vomiting REFERENCE : JMSCA9 Journal of Mental Science. (London, UK) V.4-108, 1857-1962. For publisher information, see BJPYAJ. Volume(issue)/page/year: 101,317,1955 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 149 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 240 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 23 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Gastrointestinal - nausea or vomiting REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Primate - monkey DOSE/DURATION : 31 mg/kg TOXIC EFFECTS : Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - nausea or vomiting REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 172 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973