34816-55-2

• 常用中文名：甲氧炔雌醇
• 常用英文名：Moxestrol
• CAS号：34816-55-2
• 分子式：C₂₁H₂₆O₃
• 分子量：326.42900
• 发布时间：2018-07-06 11:30:11
• 更新时间：2024-01-14 11:51:16

名称

• 中文名: 甲氧炔雌醇
• 英文名: (8S,9S,11S,13S,14S,17R)-17-ethynyl-11-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
• 英文别名: 11beta-Methoxyethinylestradiol; Moxestrolum; Moxestrol; RU 2858

物化性质

• 密度: 1.221g/cm3
• 沸点: 477.715ºC at 760 mmHg
• 分子式: C₂₁H₂₆O₃
• 分子量: 326.42900
• 闪点: 242.714ºC
• 精确质量: 326.18800
• PSA: 49.69000
• LogP: 3.23750
• 折射率: 1.609

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : RC8945000 CHEMICAL NAME : 19-Nor-17-alpha-pregna-1,3,5(10)-trien-20-yne-3,17-di ol, 11-beta-methoxy- CAS REGISTRY NUMBER : 34816-55-2 LAST UPDATED : 199612 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C21-H26-O3 MOLECULAR WEIGHT : 326.47 WISWESSER LINE NOTATION : L E5 B666TTT&J CO1 E1 FQ F1UU1 OQ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Implant SPECIES OBSERVED : Rodent - hamster DOSE/DURATION : 400 mg/kg/39W-C TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 50 ug/kg SEX/DURATION : female 16-20 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetal death Reproductive - Effects on Newborn - delayed effects TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 250 ug/kg SEX/DURATION : female 16-20 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - urogenital system TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 1250 ug/kg SEX/DURATION : female 16-20 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Newborn - live birth index (measured after birth) MUTATION DATA TEST SYSTEM : Rodent - hamster DOSE/DURATION : 160 mg/kg/20W (Continuous) REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 311,191,1994

合成路线

15084-45-4 ~% 34816-55-2

文献：Azadian Boulanger; Bertin 1973 , vol. 8, # 4 p. 451 - 454

21391-55-9 ~% 34816-55-2

文献：Azadian Boulanger; Bertin 1973 , vol. 8, # 4 p. 451 - 454

40128-89-0 ~% 34816-55-2

文献：Azadian Boulanger; Bertin 1973 , vol. 8, # 4 p. 451 - 454

21375-11-1 74-86-2 ~% 34816-55-2

文献：Azadian Boulanger; Bertin 1973 , vol. 8, # 4 p. 451 - 454

2299-08-3 ~% 34816-55-2

文献：Azadian Boulanger; Bertin 1973 , vol. 8, # 4 p. 451 - 454

上下游产品

上游产品  6
2299-08-3 15084-45-4 21391-55-9 40128-89-0
21375-11-1 74-86-2
下游产品  0