790667-49-1

• 常用中文名：1-N-boc-2(s)-甲基-哌啶-4-酮
• 常用英文名：(S)-2-Methyl-4-oxopiperidine-1-carboxylic acid tert-butyl ester
• CAS号：790667-49-1
• 分子式：C₁₁H₁₉NO₃
• 分子量：213.273
• 发布时间：2018-12-29 16:16:07
• 更新时间：2026-07-03 14:56:50

名称

• 中文名: 1-N-boc-2(s)-甲基-哌啶-4-酮
• 英文名: tert-butyl (2S)-2-methyl-4-oxopiperidine-1-carboxylate
• 中文别名: S-1-BOC-2-甲基-4-氧代哌啶; 1-N-BOC-2(S)-甲基-哌啶-4-酮; (S)-1-BOC-2-甲基哌啶-4-酮; (S)-1-BOC-2-甲基-4-哌啶酮; (2S)-2-甲基-4-氧哌啶-1-甲酸叔丁酯; S-N-叔丁氧羰基-2-甲基-4-哌啶酮; (S)-N-BOC-2-甲基-4-哌啶酮; (S)-2-甲基-4-氧代哌啶-1-羧酸叔丁酯
• 英文别名: 1-Piperidinecboxylicacid,2-methyl-4-oxo-,1,1-dimethylethyle; (2S)-2-METHYL-4-OXO-PIPERIDINE-1-CBOXYLIC ACID TERT-BUTYLESTER - PRODUCT ID; 2-methyl-4-oxo-piperidine-1-carboxylic acid tert-butyl ester; (S)-1-Boc-2-methyl-4-piperidone; tert-butyl(S)-2-methyl-4-oxopiperidine-1-cboxylate; (S)-2-Methyl-4-oxopiperidine-1-cboxylic acid tert-butyl ester; 2-Methyl-2-propanyl (2S)-2-methyl-4-oxo-1-piperidinecarboxylate; 1-N-boc-2(S)-Methyl-piperidin-4-one; (2S)-2-Methyl-4-oxo-piper; (S)-tert-Butyl2-methylpiperidine-1-cboxylate; (2S)-2-Methyl-4-oxo-piperidine-1-cboxylic acid tert-butyl ester; tert-Butyl (S)-2-Methyl-4-oxopiperidine-1-cboxylic; EOS-61954; tert-butyl (2S)-2-methyl-4-oxopiperidine-1-cboxylate; (S)-tert-Butyl 2-methyl-4-oxopiperidine-1-cboxylate; 1-Piperidinecboxylicacid, 2-methyl-4-oxo-, 1,1-dimethyleth; 1-Piperidinecboxylic acid, 2-methyl-4-oxo-, 1,1-dimethylethyl ester, (2S); 1-Piperidinecboxylicacid,2-methyl-4-oxo-,1,1-dimethylethylester,(2S)-(9CI)

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 298.8±33.0 °C at 760 mmHg
• 分子式: C₁₁H₁₉NO₃
• 分子量: 213.273
• 闪点: 134.5±25.4 °C
• 精确质量: 213.136490
• PSA: 46.61000
• LogP: 0.88
• 蒸汽压: 0.0±0.6 mmHg at 25°C
• 折射率: 1.471
• 储存条件: 2-8°C，干燥

安全

• 危害码 (欧洲): Xi

合成路线

790667-45-7 24424-99-5 ~96% 790667-49-1

文献：ELI LILLY AND COMPANY Patent: WO2004/94380 A1, 2004 ; Location in patent: Page 28; 31-32 ; WO 2004/094380 A1

921599-74-8 24424-99-5 ~99% 790667-49-1

文献：PFIZER INC.; Brodney, Michael Aaron; Efremov, Ivan Viktorovich; Helal, Christopher John; O'Neill, Brian Thomas Patent: US2013/150376 A1, 2013 ; Location in patent: Paragraph 0270 ;

71322-99-1 24424-99-5 ~% 790667-43-5 790667-49-1

文献：Schering Corporation Patent: US2005/4121 A1, 2005 ; Location in patent: Page/Page column 12 ; US 20050004121 A1

190906-92-4 ~35% 790667-43-5 790667-49-1

文献：ELI LILLY AND COMPANY Patent: WO2004/94380 A1, 2004 ; Location in patent: Page 26-27 ; WO 2004/094380 A1

10575-36-7 ~% 790667-49-1

文献：NOVARTIS AG; MILTZ, Wolfgang; OBERHAUSER, Berndt; VAUPEL, Andrea; VELCICKY, Juraj; WEIGAND, Klaus; LELETI, Rajender Reddy; LIU, Yugang; DU, Zhengming Patent: US2012/252778 A1, 2012 ; US 20120252778 A1

24424-99-5 89467-36-7 ~15% 790667-49-1

文献：ELI LILLY AND COMPANY Patent: WO2004/94380 A1, 2004 ; Location in patent: Page 28; 31-32 ; WO 2004/094380 A1

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