149140-54-5

• 常用中文名：(3R,4S)-4-苯基-3-[(三乙基硅烷基)氧基]-2-氮杂环丁酮
• 常用英文名：(3R,4S)-4-Phenyl-3-[(Triethylsilyl)Oxy]-2-Azetidinone
• CAS号：149140-54-5
• 分子式：C₁₅H₂₃NO₂Si
• 分子量：277.43400
• 发布时间：2017-05-26 14:24:32
• 更新时间：2026-07-27 13:09:23

名称

• 中文名: (3R,4S)-4-苯基-3-[(三乙基硅烷基)氧基]-2-氮杂环丁酮
• 英文名: (3R,4S)-4-phenyl-3-triethylsilyloxyazetidin-2-one
• 中文别名: 多烯紫杉醇/侧链硅化物(不含保护基); 卡巴他赛杂质57; 三尖杉宁杂质7; 多烯紫杉醇/侧链硅化物
• 英文别名: 2-Azetidinone,4-phenyl-3-[(triethylsilyl)oxy]-, (3R,4S); (3R,4S)-3-[(Triethylsilyl)oxy]-4-phenyl-2-azetidinone; (3R-cis)-4-Phenyl-3-[(triethylsilyl)oxy]-2-azetidinone; Cabazitaxel Impurity 57; 4-phenyl-3-triethylsilanyloxy-azetidin-2-one; Chalomannine Impurity 7; Polyene paclitaxel/side chain silicides (without protective oups); (3R,4S)-4-Phenyl-3-[(triethylsilyl)oxy]-2-azetidinone

物化性质

• 密度: 1.04g/cm3
• 沸点: 393.216ºC at 760 mmHg
• 分子式: C₁₅H₂₃NO₂Si
• 分子量: 277.43400
• 闪点: 191.611ºC
• 精确质量: 277.15000
• PSA: 41.82000
• LogP: 3.52380
• 蒸汽压: 0mmHg at 25°C
• 折射率: 1.516

合成路线

994-30-9 132127-34-5 ~97% 149140-54-5

文献：Walker; Swigor; Kant; Schroeder Journal of Labelled Compounds and Radiopharmaceuticals, 1994 , vol. 34, # 10 p. 973 - 980

350583-44-7 ~60% 149140-54-5

文献：Beusker, Patrick H.; Veldhuis, Harald; Van Den Bossche, Bianca A. C.; Scheeren, Hans W. European Journal of Organic Chemistry, 2001 , # 9 p. 1761 - 1768

288-32-4 930-21-2 994-30-9 ~% 149140-54-5

文献：US5254580 A1, ;

994-30-9 ~% 149140-54-5

文献：European Journal of Organic Chemistry, , # 9 p. 1761 - 1768

99458-15-8 ~% 149140-54-5

文献：European Journal of Organic Chemistry, , # 9 p. 1761 - 1768

350583-35-6 ~% 149140-54-5

文献：European Journal of Organic Chemistry, , # 9 p. 1761 - 1768

144790-01-2 ~% 149140-54-5

文献：Tetrahedron Letters, , vol. 39, # 21 p. 3559 - 3562

208848-58-2 ~% 149140-54-5

文献：Tetrahedron Letters, , vol. 39, # 21 p. 3559 - 3562

132127-31-2 ~% 149140-54-5

文献：Tetrahedron Letters, , vol. 34, # 26 p. 4149 - 4152

上下游产品

上游产品  8
994-30-9 132127-34-5 288-32-4 930-21-2
350583-35-6 144790-01-2 208848-58-2 132127-31-2
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149198-47-0 149249-91-2