166895-06-3

• 常用中文名：4-(4-fluorophenyl)-5-pyridin-4-yl-1,3-oxazole
• 常用英文名：4-(4-fluorophenyl)-5-pyridin-4-yl-1,3-oxazole
• CAS号：166895-06-3
• 分子式：C₁₄H₉FN₂O
• 分子量：240.23200
• 发布时间：2017-10-16 00:57:02
• 更新时间：2024-01-12 11:11:49

名称

• 英文名: 4-(4-fluorophenyl)-5-pyridin-4-yl-1,3-oxazole
• 英文别名: Pyridine deriv. 9; 4-(4-Fluorophenyl)-5-(4-pyridyl)oxazole; 4-[4-(4-fluoro-phenyl)-oxazol-5-yl]-pyridine; 4-(4-Fluorophenyl)-5-(pyridin-4-yl)oxazole; Pyridine,4-[4-(4-fluorophenyl)-5-oxazolyl]

物化性质

• 分子式: C₁₄H₉FN₂O
• 分子量: 240.23200
• 精确质量: 240.07000
• PSA: 38.92000
• LogP: 3.54270

合成路线

872-85-5 165806-95-1 ~60% 166895-06-3

文献：McClure, Kim F.; Abramov, Yuriy A.; Laird, Ellen R.; Barberia, John T.; Cai, Weiling; Carty, Thomas J.; Cortina, Santo R.; Danley, Dennis E.; Dipesa, Alan J.; Donahue, Kathleen M.; Dombroski, Mark A.; Elliott, Nancy C.; Gabel, Christopher A.; Han, Seungil; Hynes, Thomas R.; LeMotte, Peter K.; Mansour, Mahmoud N.; Marr, Eric S.; Letavic, Michael A.; Pandit, Jayvardhan; Ripin, David B.; Sweeney, Francis J.; Tan, Douglas; Tao, Yong Journal of Medicinal Chemistry, 2005 , vol. 48, # 18 p. 5728 - 5737

872-85-5 165806-85-9 ~17% 166895-06-3

文献：SmithKline Beecham Corporation Patent: US6288062 B1, 2001 ;

77287-34-4 216529-31-6 ~14% 166895-06-3

文献：Seerden, Jean-Paul G.; Leusink-Ionescu, Gabriela; Leguijt, Robin; Saccavini, Catherine; Gelens, Edith; Dros, Bas; Woudenberg-Vrenken, Titia; Molema, Grietje; Kamps, Jan A.A.M.; Kellogg, Richard M. Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 5 p. 1352 - 1357

403-43-0 ~% 166895-06-3

文献：Seerden, Jean-Paul G.; Leusink-Ionescu, Gabriela; Leguijt, Robin; Saccavini, Catherine; Gelens, Edith; Dros, Bas; Woudenberg-Vrenken, Titia; Molema, Grietje; Kamps, Jan A.A.M.; Kellogg, Richard M. Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 5 p. 1352 - 1357

6576-05-2 ~% 166895-06-3

文献：Seerden, Jean-Paul G.; Leusink-Ionescu, Gabriela; Leguijt, Robin; Saccavini, Catherine; Gelens, Edith; Dros, Bas; Woudenberg-Vrenken, Titia; Molema, Grietje; Kamps, Jan A.A.M.; Kellogg, Richard M. Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 5 p. 1352 - 1357

116332-54-8 ~% 166895-06-3

文献：Seerden, Jean-Paul G.; Leusink-Ionescu, Gabriela; Leguijt, Robin; Saccavini, Catherine; Gelens, Edith; Dros, Bas; Woudenberg-Vrenken, Titia; Molema, Grietje; Kamps, Jan A.A.M.; Kellogg, Richard M. Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 5 p. 1352 - 1357